01897

Adenosine 5′-diphosphate disodium salt

≥90%

• Synonym(s): 5′-ADP-Na₂
• Empirical Formula (Hill Notation): C₁₀H₁₃N₅Na₂O₁₀P₂
• CAS Number: 16178-48-6
• Molecular Weight: 471.16
• Beilstein: 7563620
• Numéro EC: 240-314-7
• Numéro MDL: MFCD00066635
• eCl@ss: 32160414
• ID de substance PubChem: 329747370
• NACRES: NA.51

Properties

• Essai: ≥90%
• Forme: powder or crystals
• Activité optique: [α]20/D −29.6±1°, c = 0.5% in 0.5 M Na₂HPO₄
• Impuretés: ≤10% water
• Temp. de stockage: −20°C
• SMILES string: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: ORKSTPSQHZNDSC-IDIVVRGQSA-L

Description

Application

Adenosine 5′-diphosphate disodium salt has been used as a purinergic G protein-coupled receptor P2Y12 agonistin platelet activation tests in blood samples.

Actions biochimiques/physiologiques

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y₁ and P2Y₁₂. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Safety Information

• Code de la classe de stockage: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Point d'éclair C: Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)