G7127

Guanosine 5′-diphosphate sodium salt

Type I, ≥96% (HPLC)

• Synonym(s): GDP
• Empirical Formula (Hill Notation): C₁₀H₁₅N₅O₁₁P₂
• CAS Number: 43139-22-6
• Molecular Weight: 443.20
• Numéro MDL: MFCD00070121
• ID de substance PubChem: 24895291
• NACRES: NA.51

Properties

• Type: Type I
• Niveau de qualité: 300
• Essai/Dosage: ≥96% (HPLC)
• Expédié(e)(s) dans: dry ice
• Temp. de stockage: −20°C
• SMILES string: [Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)c2N1
• InChI: 1S/C10H15N5O11P2.Na.H/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;
• InChI key: PVMPTWQLNDHIEV-UHFFFAOYSA-N

Description

Application

Guanosine 5′-diphosphate sodium salt has been used:

• in GTP-γ-35S functional assays
• in Y1 agonist-stimulated [35S]- guanosine-5′-O-(3-thio)triphosphate (GTPγS) functional binding
• in the expression and purification of recombinant proteins

Actions biochimiques/physiologiques

Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

Safety Information

• Code de la classe de stockage: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Point d'éclair C: Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)