Rabbit anti-MSH2 Antibody, Affinity Purified

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FCC1, mutS homolog 2, LCFS2, COCA1, MutS protein homolog 2, HNPCC, nonpolyposis type 1, nonpolyposis type 1 (E. coli), HNPCC1, mutS (E. coli) homolog 2 (colon cancer; nonpolyposis type 1), colon cancer, hMSH2

Source biologique


Niveau de qualité


Forme d'anticorps

affinity purified immunoglobulin

antibody product type

primary antibodies


Powered by Bethyl Laboratories, Inc.

species reactivity

human, mouse


immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:1,000-1:5,000

N° d'accession


N° d'accession UniProt

Expédié(e)(s) dans

wet ice

Temp. de stockage


Gene Information

rabbit ... MSH2(4436)


The epitope recognized by PLA0106 maps to a region between residues 1 and 50 of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).

Forme physique

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Autres remarques

MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


NONH for all modes of transport

WGK Allemagne


Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

Certificat d'analyse
Certificat d'origine
Raul Alvarado-Bachmann et al.
Molecular medicine reports, 10(2), 1003-1006 (2014-05-27)
Knowledge of the molecular biology of primary colorectal cancer (CRC) has improved in recent years, and one reason for this is the identification of microsatellite instability (MSI), which occurs in up to 15% of sporadic CRC. However, less is known...
Kimberly C Wiegand et al.
Human pathology, 45(6), 1258-1268 (2014-04-29)
ARID1A/BAF250a has been recently implicated as a tumor suppressor in gastric cancer. We sought to clarify the clinical significance of BAF250a/ARID1A in relation to other clinical parameters and relevant biomarkers in gastric carcinoma. Cases from 2 separate cohorts of patients...
Anne-Sophie Bats et al.
Anticancer research, 34(6), 3211-3215 (2014-06-13)
To assess the feasibility of Microsatellite Instability (MSI) analysis in uterine cavity washings for detecting endometrial cancer in Lynch syndrome. This was a proof-of-concept study in Lynch syndrome patients, scheduled for hysterectomy. At the beginning of surgical procedure, uterine cavity...

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