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Cell signaling

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facet applications:Cell signaling
facet content type:Technical Article
Introduction about α-Actinin protein present in both muscle and non-muscle cells.
Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere
Cholesterol Biosynthesis Regulation
The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. LDL receptors regulate the cellular transport of lipid rich low density lipoprotein (LDL) particles.
Interleukin Family (IL)
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and
Melatonin Receptors
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Vascular Endothelial Growth Factors (VEGF)
Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF-A (VEGF) is a potent growth factor for blood vessel endothelial cells, showing pleiotropic
Vimentin is an intermediate filamentous cytosketetal protein found in cells of mesenchymal origin. Vimentin typically exists as a coiled-coil dimer that interacts with another dimers to form a tetrameric complex that forms cytoskeletal protein sheets
Vitronectin is a glycoprotein present in plasma and tissues. Together with fibronectin, vitronectin is one of the major cell adhesion proteins in plasma.
VEGF Pathway
Read review on VEGF signaling pathway (Vascular endothelial growth factor (VEGF)/VEGF receptor) and find related products.
GABAB Receptors
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Insulin-like Growth Factors (IGF)
Insulin-like Growth Factors (IGF)
Mitochondrial Stress and ROS
Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.
Review of O-Linked Glycoproteins
O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.
The AMP-activated protein kinase (AMPK) acts as a sensor of cellular energy status. AMPK exists as heterotrimeric complexes comprising a catalytic α subunit and regulatory β and γ subunits.
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Protein Kinase C (PKC)
Protein kinase C (PKC) is an AGC kinase that phosphorylates serine and threonine residues in many target proteins.
Phosphoprotein Phosphatases (Serine/Threonine)
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Phospholipase A2
Phospholipase A2 (PLA2) designates a class of enzymes that hydrolyze the sn-2 ester of glycerophospholipids to produce a fatty acid and a lysophospholipid. It has become clear that some of these enzymes liberate arachidonic acid in mammalian cells for the
Phospholipase D
Phosphatidylcholine (PC)-specific phospholipase D (PLD) enzymes catalyze the hydrolysis of PC to generate choline and phosphatidic acid. These enzymes belong to a superfamily of phosphatidyltransferases with a characteristic unique duplicated catalytic domain motif, the PLD or " HKD"
Lipopolysaccharides for Research – Structure, Function & Applications
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
Sodium Channels
Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.
Calcium Channels
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Adenosine Receptors
We offers many products related to adenosine receptors for your research needs.
Focal Adhesion Kinase (FAK) Overview
The focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase. FAK has been implicated as a downstream signaling molecule that functions in the control of several integrin-regulated biological processes.
The extracellular signal regulated kinase (ERK1 and ERK2) pathways are activated by mitogens and play an important role in controlling cell growth and differentiation.
Glutamate Receptors (Ion Channel Family)
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Acetylcholine Receptors (Nicotinic)
Sigma-Aldrich offers many products related to nicotinic acetylcholine receptors for your research needs.
Acetylcholine Synthesis and Metabolism
Acetylcholine is synthesized from acetyl coenzyme A and choline by the enzyme choline acetyltransferase. In addition to its synthesis in the liver, choline employed in acetylcholine production is derived from dietary sources.
Acetylcholine Receptors (Muscarinic)
Muscarinic acetylcholine receptors are G protein-coupled receptors (GPCRs) and mediate acetylcholine actions in the CNS and non-nervous tissues. Learn more about acetylcholine receptors and their role in cell signaling.
Neurotensin Receptors
Neurotensin is a 13 amino acid regulatory peptide found mainly in gut and brain. Intestinal neurotensin is produced by a discrete population of endocrine cells (N cells) scattered throughout the jejuno-ileal mucosa.
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