ASGCT 2025

May 13-16, 2025, New Orleans, Louisiana

The American Society of Gene and Cell Therapy’s (ASGCT) Annual Meeting is the premier event for professionals in gene and cell therapy. Visit us at booth 1237 to learn about our integrated products, manufacturing and testing to help advance your therapy to patients.

Don't miss our presentations featured during the week: 

Wednesday, May 14th 

8:00 - 8:30 am - Room 271-273 - Symposium presentation

Title: Optimizing AAV gene therapies: NGS applications to enhance development, manufacturing, and testing
Speakers: Brianna McManus, Senior Associate Scientist and Kelly Rios, Ph.D., Analytical Development Scientist

2:00 - 2:15 pm - Tools and Technology Forum presentation 

Title: Harnessing Innovative Technologies for Enhancing AAV Production
Speaker: Megan Del Greco, Research Scientist III, USP Templates & Scale Up

Thursday, May 15th

4:45 - 5:00 pm - NOLA Theater C - Oral Abstracts

Title: Enhanced AAV Capture Using Membrane Chromatography and Optimized Mid-Stream Processing
Speaker: Thibaut Deschamps

Friday, May 16th

8:30 - 9:00 am - Room 383-385 - Symposium presentation 

Title: To 1000L and Beyond: Introducing the first-and-only transfection complex stabilizer for simple AAV manufacturing scale-up 
Speaker: Laura Juckem, Ph.D., Vice President, Research and Development

Engage with our poster authors in Poster Hall I2:  

Tuesday, May 13th - 6:00 – 7:30 pm 

• Increasing rAAV Productivity and Product Quality Through Selection of a High Producing HEK293 Cell Line and Enhancer Addition
• A Scalable, DoE-based Approach to Improving Plasmid Ratios for AAV Transfection 

Wednesday, May 14th – 5:30 – 7:00 pm

• Methods to Improve the Clarification Process of AAV Therapy Manufacturing
• Affinity purification analysis: a comparison of AAV2 and AAV5 serotypes
• Next-Generation Sequencing for AAV Characterization
• Multiplex ddPCR Approach as Proof-of-Principle for Accurate AAV Genome Integrity Assessment and Enhanced Vector Production

Thursday, May 15th – 5:30 – 7:00 pm 

• Strategies for Overcoming Analytical Challenges in Complex Upstream AAV Samples
• Importance of AAV sample preparation for gc/mL titer determination using PCR
• Utilization of Real-time Multi-angle Light Scattering (RT-MALS) for Accelerated AAV Chromatography Development
• High-Throughput Flow Cytometry Assay for Quantifying Infectivity of AAV, Adenovirus, and Lentivirus Vectors in Gene Therapy Application
• Optimizing Upstream Process Inputs to Enhance Viral Yields and Ensure Product Quality in Adeno-Associated Virus (AAV) Manufacturing
• Process Optimization of a Baculovirus-Insect Cell Expression System for Scalable rAAV Production