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160660

Quinaldic acid

98%

Synonym(s):

2-Quinolinecarboxylic acid

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2.5 g
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£29.20
10 g
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£34.70

About This Item

Empirical Formula (Hill Notation):
C10H7NO2
CAS Number:
Molecular Weight:
173.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-218-3
Beilstein/REAXYS Number:
126322
MDL number:
Assay:
98%
Form:
solid

£29.20


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Quality Level

assay

98%

form

solid

mp

156-158 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2ccccc2n1

InChI

1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13)

InChI key

LOAUVZALPPNFOQ-UHFFFAOYSA-N

General description

Quinaldic acid is also referred as quinoline-2-carboxylic acid. Microwave-assisted preparation of substituted anilides of quinaldic acid has been reported.[1] It inhibits the oxidation of pyruvate, α-ketoglutarate, glutamate and citrate in rat liver mitochondria.[2] Quinaldic acid is a metabolite of tryptophan degradation and inhibits the gluconeogenesis in perfused livers.[2]

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This Item
22550280348P1386
assay

98%

assay

≥95.0% (GC)

assay

97%

assay

≥99.5%

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

200

form

solid

form

liquid

form

-

form

-

mp

156-158 °C (lit.)

mp

−9-−3 °C (lit.)

mp

-

mp

−24-−23 °C (lit.)

functional group

carboxylic acid

functional group

-

functional group

bromo, carboxylic acid

functional group

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Pavel Bobal et al.
Molecules (Basel, Switzerland), 17(2), 1292-1306 (2012-02-02)
In this study a one step method for the preparation of substituted anilides of quinoline-2-carboxylic acid was developed. This efficient innovative approach is based on the direct reaction of an acid or ester with substituted anilines using microwave irradiation. The
Stereocontrolled synthesis of the quinaldic acid macrocyclic system of thiostrepton.
K C Nicolaou et al.
Angewandte Chemie (International ed. in English), 41(11), 1937-1940 (2002-06-03)
K Jhamandas et al.
Brain research, 529(1-2), 185-191 (1990-10-08)
Certain products of tryptophan metabolism interact with excitatory amino acid receptors to produce or protect against excitotoxicity. In this study, the action of several tryptophan metabolites, yielded by the kynurenine pathway, on cortical cholinergic toxicity was evaluated following focal injection



Global Trade Item Number

SKUGTIN
160660-2.5G04061833464533
160660-10G04061838346360

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