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Merck

196479

Sigma-Aldrich

2-Phenyl-4-quinolinecarboxylic acid

99%

Synonym(s):

2-Phenylcinchoninic acid, Cinchophen

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50 G
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About This Item

Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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Quality Level

Assay

99%

form

powder

mp

214-215 °C (lit.)

solubility

alcohol: soluble 1g in 120ml(lit.)
chloroform: soluble 1g in 400ml(lit.)
diethyl ether: soluble 1g in 100ml(lit.)
water: insoluble(lit.)

SMILES string

OC(=O)c1cc(nc2ccccc12)-c3ccccc3

InChI

1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)

InChI key

YTRMTPPVNRALON-UHFFFAOYSA-N

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1 of 4

This Item
14788513468247871
assay

99%

assay

99%

assay

≥97.0% (HPLC)

assay

99%

solubility

alcohol: soluble 1g in 120ml(lit.), diethyl ether: soluble 1g in 100ml(lit.), chloroform: soluble 1g in 400ml(lit.), water: insoluble(lit.)

solubility

alcohol: freely soluble, benzene: freely soluble, chloroform: freely soluble, diethyl ether: freely soluble, petroleum ether: very slightly soluble, water: very slightly soluble

solubility

-

solubility

water: soluble 1g in 1475ml(lit.), alcohol: freely soluble(lit.), diethyl ether: freely soluble(lit.), hot water: soluble(lit.)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

214-215 °C (lit.)

mp

39-42 °C (lit.)

mp

-

mp

228-230 °C (lit.)

form

powder

form

solid

form

powder

form

-

General description

2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid[1].

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Amides and hydrazides of aroylpyrivic acids. Part 6 Synthesis and study of antiinflammatory and analgesic activity of ?-aroylpyruvoyl hydrazides of 2-methyl (phenyl)-4-quinolinecarboxylic acids.
Milyutin AV, et al.
Pharmaceutical Chemistry Journal, 32(8), 422-424 (1998)
[DISTRIBUTION AND CONTENT OF RIBONUCLEOPROTEINS IN THE SMALL INTESTINE MUCOUS MEMBRANE IN CHRONIC EXPERIMENTAL STOMACH ULCER IN DOGS].
S A DALIMOV et al.
Meditsinskii zhurnal Uzbekistana, 39, 50-53 (1963-08-01)
[Gout].
Y OSHIMA
Naika. Internal medicine, 10, 1101-1102 (1962-12-01)
[Contributions to evaluation of the substances inhibiting inflammation].
F VARGA et al.
Acta physiologica Academiae Scientiarum Hungaricae, 23, 69-78 (1963-01-01)
H Jingu et al.
Neuroreport, 7(15-17), 2649-2653 (1996-11-04)
This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the

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