23261
Trichloromethyl chloroformate
≥97.0% (GC)
Synonym(s):
TCF, Diphosgene, di-Phosgene
About This Item
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Quality Level
Assay
≥97.0% (GC)
refractive index
n20/D 1.458
bp
20 °C/10 mmHg (lit.)
density
1.639 g/mL at 20 °C
storage temp.
2-8°C
SMILES string
ClC(=O)OC(Cl)(Cl)Cl
InChI
1S/C2Cl4O2/c3-1(7)8-2(4,5)6
InChI key
HCUYBXPSSCRKRF-UHFFFAOYSA-N
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Related Categories
Application
- Cyclic carbamimidates using a monophosphine gold(i) catalyst
- N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands
- Prostate-specific membrane antigen-targeted anticancer prodrugs
- Potential west nile virus protease inhibitors
- Antibody-drug conjugates (ADCs)
- Erythromycin A derivatives
TCF can also be used:
- To synthesize N-carboxy α-amino acid anhydrides.
- As an acylating agent to synthesize oxazolidinones from α-amino alcohols.
- As a dehydrating agent to synthesize aromatic diisocyanides in the presence of triethylamine.
Other Notes
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Skin Corr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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