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417963

Sigma-Aldrich

Chitosan

from shrimp shells, practical grade

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Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
CAS Number:
MDL number:
NACRES:
NA.23

biological source

shrimp shells

Quality Level

grade

practical grade

form

solid

mol wt

190000-375000 Da

viscosity

>200 cP, 1 wt. % in 1% acetic acid(20 °C, Brookfield)(lit.)

solubility

1 M acetic acid: 10 mg/mL

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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This Item
448877423441105508
vibrant-m

417963

Chitosan

vibrant-m

448877

Chitosan

vibrant-m

42344

Chitosan

vibrant-m

1105508

Chitosan

biological source

shrimp shells

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

solubility

1 M acetic acid: 10 mg/mL

solubility

dilute aqueous acid: soluble

solubility

-

solubility

-

form

solid

form

powder

form

-

form

-

mol wt

190000-375000 Da

mol wt

-

mol wt

Mw 141 kDa

mol wt

-

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

≥ 75% deacetylated

Storage Class Code

11 - Combustible Solids

WGK

nwg

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Arash Ghalayani Esfahani et al.
Journal of biomedical materials research. Part A, 107(7), 1455-1465 (2019-02-21)
One of the main challenges in the design of scaffolds for cortical bone regeneration is mimicking the highly oriented, hierarchical structure of the native tissue in an efficient, simple, and consistent way. As a possible solution to this challenge, positive
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino
William D Stanish et al.
The Journal of bone and joint surgery. American volume, 95(18), 1640-1650 (2013-09-21)
Microfracture, the standard of care, is recognized to be an incomplete solution for cartilage damage. BST-CarGel, a chitosan-based medical device, is mixed with autologous whole blood and is applied to a microfractured cartilage lesion in which it physically stabilizes the
Electrochemical biosensor applications of polysaccharides chitin and chitosan.
Wipa Suginta et al.
Chemical reviews, 113(7), 5458-5479 (2013-04-06)
Gregory H Bird et al.
The Journal of clinical investigation, 124(5), 2113-2124 (2014-04-20)
Respiratory syncytial virus (RSV) infection accounts for approximately 64 million cases of respiratory disease and 200,000 deaths worldwide each year, yet no broadly effective prophylactic or treatment regimen is available. RSV deploys paired, self-associating, heptad repeat domains of its fusion

Articles

The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processing parameters on the ability to control the size and distribution of chitosan based microparticles, targeting diameter range of 1-10 µm. The effect of encapsulating bovine serum albumin (BSA), a model protein, as well as sodium tripolyphosphate (TPP), a cross-linker, was studied.

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

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