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448877

Sigma-Aldrich

Chitosan

medium molecular weight

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Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
CAS Number:
MDL number:
NACRES:
NA.23

form

powder

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

dilute aqueous acid: soluble

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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This Item
44886941941942344
vibrant-m

448877

Chitosan

vibrant-m

448869

Chitosan

vibrant-m

419419

Chitosan

vibrant-m

42344

Chitosan

solubility

dilute aqueous acid: soluble

solubility

dilute aqueous acid: soluble

solubility

H2O: insoluble, organic solvents: insoluble

solubility

-

form

powder

form

powder

form

(Coarse ground flakes and powder)

form

-

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

20-300 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

-

Application

Chitosan may be used as a flocculant, in protein precipitation, encapsulating agent and aqueous thickener.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

75-85% deacetylated

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Viviana Vergaro et al.
International journal of biological macromolecules, 99, 187-195 (2017-02-25)
Carbohydrate polimeric microcapsules were assembled using a LbL approach onto a CaCO
Mohammad Amin Shamekhi et al.
International journal of biological macromolecules, 127, 396-405 (2019-01-10)
Enhancement of physical and mechanical properties of the scaffolds is achieved via various methods including cross-linking and incorporation of nano particles. In the present research chitosan-based scaffolds firstly were reinforced with the incorporation of the graphene oxide (GO) nanoparticles. The
Arnout Mieremet et al.
PloS one, 12(3), e0174478-e0174478 (2017-03-24)
Full thickness human skin models (FTMs) contain an epidermal and a dermal equivalent. The latter is composed of a collagen dermal matrix which harbours fibroblasts. Current epidermal barrier properties of FTMs do not fully resemble that of native human skin
Wei-Hsuan Lo et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-07)
(1) Background: Few antifungal drugs are currently available, and drug-resistant strains have rapidly emerged. Thus, the aim of this study is to evaluate the effectiveness of the antifungal activity from a combinational treatment of chitosan with a clinical antifungal drug
Paulo V O Toledo et al.
International journal of biological macromolecules, 123, 1180-1188 (2018-11-24)
Xanthan gum (XG) was applied for the creation of hydrophilic, hydrophobic and layered cryogels. Firstly, the correlation among synthesis parameters, such as solvent composition and polymer concentration (Cp) in the precursor gel and mold diameter (Φ), with physicochemical properties and

Articles

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processing parameters on the ability to control the size and distribution of chitosan based microparticles, targeting diameter range of 1-10 µm. The effect of encapsulating bovine serum albumin (BSA), a model protein, as well as sodium tripolyphosphate (TPP), a cross-linker, was studied.

The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

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