Merck
All Photos(1)

Documents

661791

Sigma-Aldrich

(R)-(−)-COP-Cl Catalyst

Synonym(s):
Di-μ-chlorobis[η5-(R)-(pR)-2-(2′-(4′-methylethyl)oxazolinyl)cyclopentadienyl,1-C,3′-N)(η4-tetraphenylcyclobutadiene)cobalt]dipalladium, [Bis[μ-(chloro-κO:κO′)]dipalladium]bis[1,1′,1′′,1′′′-(η4-1,3-cyclobutadiene-1,2,3,4-tetrayl) tetrakis[benzene]]bis[μ-[(1-η:1,2,3,4,5-η)-2-[(4R)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl-κN3]-2,4-cyclopentadien-1-ylidene]]dicobalt
Empirical Formula (Hill Notation):
C78H66Cl2Co2N2O2Pd2
CAS Number:
Molecular Weight:
1464.98
MDL number:
PubChem Substance ID:

mp

192-208 °C

SMILES string

[Co].[Co].Cl[Pd].Cl[Pd].CC(C)[C@@H]1COC(=N1)[C]2[CH][CH][CH][CH]2.CC(C)[C@@H]3COC(=N3)[C]4[CH][CH][CH][CH]4.c5ccc(cc5)[C]6[C]([C]([C]6c7ccccc7)c8ccccc8)c9ccccc9.c%10ccc(cc%10)[C]%11[C]([C]([C]%11c%12ccccc%12)c%13ccccc%13)c%14ccccc%14

InChI

1S/2C28H20.2C11H14NO.2ClH.2Co.2Pd/c2*1-5-13-21(14-6-1)25-26(22-15-7-2-8-16-22)28(24-19-11-4-12-20-24)27(25)23-17-9-3-10-18-23;2*1-8(2)10-7-13-11(12-10)9-5-3-4-6-9;;;;;;/h2*1-20H;2*3-6,8,10H,7H2,1-2H3;2*1H;;;;/q;;;;;;;;2*+1/p-2/t;;2*10-;;;;;;/m..00....../s1

Inchi Key

FZRXGVGWPCMPTJ-TWWPWAOZSA-L

Application

Catalyst for:
  • Stereoselective allylic substitution of Z-allylic trichloroacetimidates
  • Asymmetric synthesis of allylic thiol derivatives by rearrangement of linear prochiral O-allyl carbamothioates
  • Asymmetric aza-Claisen rearrangement
  • Enantioselective preparation of allylic trichloroacetamides via rearrangement of allylic trichloroacetimidates
Catalyst employed in the rearrangement of allylic trichloracetimidates to allylic amines of high enantiopurity.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (Example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Carolyn E Anderson et al.
Journal of the American Chemical Society, 125(41), 12412-12413 (2003-10-09)
COP-Cl catalyzes the rearrangement of (E)-allylic trichloroacetimidates to provide transposed allylic trichloroacetamides of high enantiopurity, a transformation that underlies the first truly practical method for transforming prochiral allylic alcohols to enantioenriched allylic amines and congeners. The high functional group compatibility

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service