Merck
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74104

Sigma-Aldrich

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

≥96.0% (calc. on dry substance, AT)

Synonym(s):
DMTMM, MMTM
Empirical Formula (Hill Notation):
C10H17ClN4O3
CAS Number:
Molecular Weight:
276.72
Beilstein:
8026872
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥96.0% (calc. on dry substance, AT)

form

powder

reaction suitability

reaction type: Coupling Reactions

impurities

≤17 wt. % water

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

InChI key

BMTZEAOGFDXDAD-UHFFFAOYSA-M

Application

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride can be used as a condensing agent for the following transformations:
  • Condensation of carboxylic acids and amines to the corresponding amides in tetrahydrofuran.
  • Esterification of carboxylic acids with alcohols to the corresponding esters.
  • Conversion of carboxylic acids to the corresponding Weinreb amides in protic solvents.

Reagent for activating carboxylic acids in solution and solid phase peptide synthesis; superior or comparable to the most popular coupling reagents

Packaging

1 g in poly tube
5 g in poly bottle

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

198.5 °F - closed cup

Flash Point(C)

92.5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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