Merck
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A79922

Sigma-Aldrich

9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate

≥99%

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Synonym(s):
THA hydrochloride hydrate, Tacrine hydrochloride, Tetrahydroaminacrine hydrochloride hydrate
Empirical Formula (Hill Notation):
C13H14N2 · HCl · xH2O
CAS Number:
Molecular Weight:
234.72 (anhydrous basis)
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

form

solid

mp

284-286 °C (lit.)

SMILES string

O.Cl.Nc1c2CCCCc2nc3ccccc13

InChI

1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2

InChI key

PXGRMZYJAOQPNZ-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
N1626A377350280
Neocuproine hydrochloride hydrate BioReagent, crystalline

Sigma-Aldrich

N1626

Neocuproine hydrochloride hydrate

Essential+ Grade
form

solid

form

crystalline

form

powder

form

-

mp

284-286 °C (lit.)

mp

250 °C (dec.) (lit.)

mp

284-286 °C (lit.)

mp

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

Application

9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Customers Also Viewed

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A review on cholinesterase inhibitors for Alzheimer?s disease.
Anand P and Singh B
Archives of Pharmacal Research, 36(4), 375-399 (2013)
New Tacrines as Anti-Alzheimer's Disease Agents. The (Benzo) Chromeno-PyranoTacrines.
Oset-Gasque MJ and Marco-Contelles J
Current Topics in Medicinal Chemistry, 17(31), 3349-3360 (2017)
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro.
Ogura H, et al.
Methods and Findings in Experimental and Clinical Pharmacology, 22(8), 609-614 (2000)
The ameliorating effects of stigmasterol on scopolamine-induced memory impairments in mice.
Park SJ, et al.
European Journal of Pharmacology, 676(1-3), 64-70 (2012)
Acetylcholinesterase capillary enzyme reactor for screening and characterization of selective inhibitors.
da Silva JI, et al.
Journal of Pharmaceutical and Biomedical Analysis, 73, 44-52 (2013)

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