700175P

Brassicasterol

Avanti Research^™ - A Croda Brand

• Synonym(s): 24-Methyl cholest-5,22-dien-3β-ol
• Empirical Formula (Hill Notation): C₂₈H₄₆O
• CAS Number: 474-67-9
• Molecular Weight: 398.66
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 5 mg (700175P-5MG)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C
• InChI: 1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1
• InChI key: OILXMJHPFNGGTO-ZAUYPBDWSA-N

Description

General description

Brassicasterol is a plant sterol, sharing similar structure with cholesterol.[1] It is obtained through the dietary sources,[1] including sea food.[2]

Application

• Deciphering the effect of phytosterols on Alzheimer′s disease and Parkinson′s disease: the mediating role of lipid profiles: This research demonstrates the neuroprotective potential of phytosterols, including Brassicasterol, in modulating lipid profiles to mitigate symptoms of neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Guo et al., 2024).


• Liposomal Phytosterols as LDL-Cholesterol-Lowering Agents in Diet-Induced Hyperlipidemia: Discusses the effectiveness of Brassicasterol and other phytosterols encapsulated in liposomes for reducing LDL cholesterol, showcasing a potential therapeutic approach in hyperlipidemia management (Poudel et al., 2023).


• Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster: Highlights the role of Brassicasterol in regulating developmental and hormonal pathways in model organisms, suggesting implications for developmental biology studies (Wen et al., 2023).

Biochem/physiol Actions

Brassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease.[1] It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others.[3] Plant sterols can penetrate through the blood brain barrier.[4]

Packaging

5 mL Amber Glass Screw Cap Vial (700175P-5MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable