Merck
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1.16886

Millipore

Fractogel® EMD COO⁻ (M)

weak cation exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

Quality Level

sterility

sterile (Caustic Stable)

form

resin

specific analyte(s)

MAbs

parameter

300 cm/hr flow rate
8 bar max. pressure

matrix active group

methacrylate

mean particle size

40-90 μm

capacity

100 mg binding capacity (lysozyme/ml of resin)

transition temp

flash point 35 °C (calculated)

density

1.43 g/cm3 at 20 °C

separation technique

cation exchange

storage temp.

2-30°C

Packaging

  • 1.16886.0100: Fractogel® EMD COO- (M) Resin 100ml
  • 1.16886.0010: Fractogel® EMD COO- (M) Resin 10ml
  • 1.16886.0500: Fractogel® EMD COO- (M) Resin 500ml
  • 1.16886.5000: Fractogel® EMD COO- (M) Resin 5L

Analysis Note

Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.05 %
Cerium: ≤ 10 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.30
Functional test (c:d): ≤ 0.70
Functional test: Separation of chymotrypsinogen A, cytochrome C and lysozyme

Legal Information

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

95.0 °F

Flash Point(C)

35 °C

Certificate of Analysis

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Certificate of Quality

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