Merck

1.37112

SAFC

Poloxamer 188

EMPROVE® EXPERT, (stabilized with 70ppm BHT), Ph. Eur., NF

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
Polyethylene glycol, propoxylated
Linear Formula:
(C3H6O · C2H4O)x
CAS Number:
MDL number:

Agency

NF
Ph. Eur.

Quality Level

product line

EMPROVE® EXPERT

form

solid

technique(s)

API processing | nano-milling: suitable

pH

5-7.5 (20 °C, 10 g/L in H2O)

mp

52 °C

transition temp

flash point 260 °C

density

1.06 g/cm3 at 70 °C

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

2-25°C

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1.370971.371721.07478
Poloxamer 188 EMPROVE® EXPERT, (stabilized with 70ppm BHT), Ph. Eur., NF

SAFC

1.37112

Poloxamer 188

Polysorbate 20 high purity, EMPROVE® EXPERT, Ph. Eur., ChP, JPE, NF

SAFC

1.37172

Polysorbate 20

1,2-Propanediol EMPROVE® EXPERT, Ph. Eur., BP, USP

SAFC

1.07478

1,2-Propanediol

form

solid

form

-

form

liquid

form

liquid

technique(s)

API processing | nano-milling: suitable

technique(s)

-

technique(s)

-

technique(s)

-

mp

52 °C

mp

52 °C

mp

98.9 °C

mp

-59 °C

transition temp

flash point 260 °C

transition temp

flash point 260 °C

transition temp

-

transition temp

flash point 99 °C

density

1.06 g/cm3 at 70 °C

density

1.06 g/cm3 at 70 °C

density

1.1 g/cm3 at 25 °C

density

1.04 g/cm3 at 20 °C

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Poloxamer 188 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.
Due to its low microbial and endotoxin limits, Poloxamer 188 Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 8

1 of 8

Trehalose dihydrate EMPROVE® EXPERT, Ph. Eur., ChP, NF, JP

SAFC

1.02776

Trehalose dihydrate

Acetonitrile EMPROVE® ESSENTIAL

SAFC

1.37134

Acetonitrile

Poloxalene United States Pharmacopeia (USP) Reference Standard

USP

1546106

Poloxalene

Poloxamer 407 purified, non-ionic

Sigma-Aldrich

16758

Poloxamer 407

Poloxamer liquid United States Pharmacopeia (USP) Reference Standard

USP

1546150

Poloxamer liquid

TWEEN® 20 (Polysorbate) EMPROVE® ESSENTIAL, Ph. Eur., JPE, NF

SAFC

8.17072

TWEEN® 20 (Polysorbate)

Poloxamer 124 European Pharmacopoeia (EP) Reference Standard

P2163920

Poloxamer 124

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service