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CAX2-S0000

Millipore

CellASIC ONIX2 Microfluidic System

eCl@ss:
32011202

W × D × H

330 mm × 306 mm × 108 mm

shipped in

ambient

General description

CellASIC® ONIX2 Microfluidic System is an automated platform for precise manipulation of multiple key cell culture parameters, enabling measurement of cellular responses to pre-programmed media, temperature, and gas environment changes. It provides detailed information about live cell processes with ultra-high quality images and complete environment control. The system utilizes high quality, optically clear microfluidic plates and intuitive software, while integrating with a broad range of inverted microscopes to allow continuous, high magnification observation of live cells—as they react to their environment in time.

Includes:
  • Controller System: Small footprint, integrated microincubator controller maintains fluid movement, reagent additions, temperature, and gas conditions.
  • Microfluidic Plates: Application specific plates bring new cell culture capabilities for live cell imaging.
  • Manifold: Low-profile, high quality, high optical clarity culture chambers and manifold, mount easily on an inverted microscope—without the need for a bulky environmental chamber.
  • Software: Intuitive software enables quick and easy set-up of detailed protocols for truly automated hands-free cell culture.

Controller System:
  • Automatically control flow rates, gas and temperature shifts, standing gradients, nutrient/drug additions, and media changes.
  • Eight critical cell culture parameters can be controlled by the system.
  • Temperature, oxygen level, growth factors, humidity, pH, osmolality, glucose, ECM and adhesion.

Advantages of the CellASIC® ONIX2 microfluidic plates:
  • High resolution imaging through optical glass bottom and chamber structures.
  • Ability to run multiple independent experiments simultaneously.
  • Continuous access to nutrients and ongoing removal of waste, promoting optimal cell health.

Manifold Advantages:
  • Manifold seals to the microfluidic plate via “one-touch” vacuum mechanism.
  • Pressure-driven flow of liquids to the cell chamber provides high precision even at very small volumes.
  • No contact between the flow system and the biological solutions (on the plate) prevents contamination.
  • Low-profile manifold is easy to adapt to any inverted microscope stage.

The software offers:
  • Clearly defined protocols with all experimental parameters saved in one file.
  • Convenience and reproducibility.
  • Consistency and reliability.
  • Error checking, self test, and data logging all make for better troubleshooting and serviceability.

Application

  • Yeast single cell response.
  • Bacterial single cell response.
  • Bacterial biofilm dynamics.
  • Cell response to hypoxic environments.
  • Cell response to changing media conditions, drugs, and other stimulants.
  • Host-pathogen interactions.
  • Chemotaxis/migration in response to chemogradient.
  • Setting optimal culture parameters for difficult cell types or long term experiments.
  • Microscopy of 3D cell culture.

Legal Information

CELLASIC is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificate of Analysis

Certificate of Origin

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