Merck
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08449

Millipore

Hemoglobin from bovine blood

suitable for microbiology

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Synonym(s):
Hb, Methemoglobin, Bovine hemoglobin
CAS Number:
9008-02-0
MDL number:
MFCD00131282
eCl@ss:
42030116
NACRES:
NA.85

Quality Level

100

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

mol wt

Mr ~64500

loss

<10% loss on drying

UniProt accession no.

P01966
P02070
P02081
P06642
P06643

application(s)

environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Neisseria spp.

Gene Information

cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

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General description

Hemoglobin is present in the red-blood corpuscles (RBCs) of vertebrates. It is composed of a globular structure with four α-β sub-units.

Application

Hemoglobin from bovine blood has been used as a supplement in tryptone yeast extract salts and glucose (TYESG) agar for performing extracellular proteolytic activity of Flavobacterium psychrophilum. It has also been used as a standard in Raman spectrometry.
The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Packaging

1 piece contains 100 g hemoglobin powder

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Quotes and Ordering

Bulk Quote-Order Product
K M Marzec et al.
The Analyst, 140(7), 2171-2177 (2014-12-24)
The composition of the lung tissue of mice was investigated using Raman confocal microscopy at 532 nm excitation wavelength and was supported with various staining techniques as well as DFT calculations. This combination of experimental and theoretical techniques allows for
Kamaljeet et al.
Frontiers in chemistry, 4, 50-50 (2017-01-26)
Synthetic dyes are a very efficient class of dyes that are ingested or come into contact with the skin from numerous sources (cosmetics, textiles, leather, paper, and drugs). An important component of their safety profile is the interactions that they
Paul Barbier et al.
Applied and environmental microbiology, 86(16) (2020-06-14)
Flavobacterium psychrophilum causes bacterial cold-water disease in wild and aquaculture-reared fish and is a major problem for salmonid aquaculture. The mechanisms responsible for cold-water disease are not known. It was recently demonstrated that the related fish pathogen, Flavobacterium columnare, requires
Rui Liu et al.
Experimental hematology, 41(7), 656-661 (2013-03-30)
Laser tweezers Raman spectroscopy was used to characterize the oxygenation response of single normal adult, sickle, and cord blood red blood cells (RBCs) to an applied mechanical force. Individual cells were subjected to different forces by varying the laser power
Edward Slone et al.
Epileptic disorders : international epilepsy journal with videotape, 14(4), 371-378 (2012-12-19)
Growing evidence suggests that focal seizures are preceded by haemodynamic changes. Specifically, changes in cerebral blood flow, blood oxygen level-dependent magnetic resonance imaging, and near-infrared spectroscopy measurements of haemoglobin have been observed in the seizure focus and other brain regions
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