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209198

Copper(II) sulfate pentahydrate

ACS reagent, ≥98.0%

Copper(II) sulfate pentahydrate

Synonym(s):

Cupric sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate

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5 g
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£24.10
100 g
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£42.50
250 g
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£64.60
500 g
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£98.50
2.5 kg
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£306.00
12 kg
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£1,160.00

About This Item

Linear Formula:
CuSO4 · 5H2O
CAS Number:
Molecular Weight:
249.69
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-847-6
MDL number:
Assay:
≥98.0%, 98.0-102.0% (ACS specification)
Grade:
ACS reagent
Form:
crystals

£24.10


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grade

ACS reagent

Quality Level

vapor pressure

7.3 mmHg ( 25 °C)

assay

≥98.0%, 98.0-102.0% (ACS specification)

form

crystals

reaction suitability

reaction type: click chemistry, reagent type: catalyst
core: copper

pH

3.5-4.5 (20 °C, 50 g/L)

mp

110 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.001%

cation traces

Ca: ≤0.005%, Fe: ≤0.003%, K: ≤0.01%, Na: ≤0.02%, Ni: ≤0.005%

SMILES string

O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O

InChI

1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2

InChI key

JZCCFEFSEZPSOG-UHFFFAOYSA-L

General description

Copper(II) sulfate pentahydrate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations. It can also act as an effective redox catalyst in combination with other mixed oxidizing agents.

Application

Copper(II) sulfate pentahydrate can be used as a catalyst:      
  • In acetylation of alcohols and phenols in the presence of acetic anhydride.      
  • To synthesize various ynamides via intramolecular coupling of amides with alkynyl bromides.

It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu2+ ion by using flame atomic absorption spectroscopy.

Features and Benefits

CuSO4.5H2O is an inexpensive, safe catalyst to be used in various organic transformations. It can also be recovered and reused in another reaction.

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This Item
C76312031651.02788
form

crystals

form

powder or crystals

form

crystals and lumps

form

fine powder

assay

≥98.0%, 98.0-102.0% (ACS specification)

assay

≥98.0%

assay

99.999% trace metals basis

assay

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

500

grade

ACS reagent

grade

-

grade

-

grade

-

pH

3.5-4.5 (20 °C, 50 g/L)

pH

3.7-4.5 (25 °C, 50 g/L)

pH

-

pH

3.5-4.5 (20 °C, 50 g/L in H2O)

mp

110 °C (dec.) (lit.)

mp

110 °C (dec.) (lit.)

mp

110 °C (dec.) (lit.)

mp

147 °C


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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids



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Copper (II) Sulfate.
Hoffman RV, et al.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
Copper (II) sulfate pentahydrate (CuSO4. 5H2O): a green catalyst for solventless acetylation of alcohols and phenols with acetic anhydride.
Heravi MM, et al.
Journal of the Brazilian Chemical Society, 17(5), 1045-1047 (2006)
Xuan Ming et al.
Cell research, 30(11), 980-996 (2020-06-26)
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question. A replication-coupled DNA methylation maintenance model was



Global Trade Item Number

SKUGTIN
209198-2.5KG04061835346585
209198-100G04061837768453
209198-5G04061837768484
209198-25KG04061833636473
209198-12KG04061838770592
209198-500G04061837768477
209198-250G04061837768460

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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