This product is synthetically produced.
L7900
Sodium DL-lactate solution
synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)
Synonym(s):
DL-Lactic acid sodium salt
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About This Item
Linear Formula:
CH3CH(OH)COONa
CAS Number:
Molecular Weight:
112.06
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-772-0
Beilstein/REAXYS Number:
4332999
MDL number:
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Product Name
Sodium DL-lactate solution, synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)
InChI key
NGSFWBMYFKHRBD-UHFFFAOYSA-M
InChI
1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
SMILES string
[Na+].CC(O)C([O-])=O
biological source
synthetic
product line
BioXtra
form
syrup
concentration
60 % (w/w)
technique(s)
cell culture | embryo: suitable
storage temp.
2-8°C
Quality Level
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This Item | L4263 | L1375 | 616702 |
|---|---|---|---|
| technique(s) cell culture | embryo: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) mass spectrometry (MS): suitable |
| concentration 60 % (w/w) | concentration 27-33% (enzymatic), 60 % (w/w) | concentration 60 % (w/w) | concentration 45-55 % (w/w) in H2O |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| product line BioXtra | product line BioReagent | product line - | product line - |
| form syrup | form syrup | form syrup | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
Application
Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
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Product No.
Description
Pricing
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
Influence of lactate and acetate salt adaptation on Salmonella Typhimurium acid and heat resistance.
Wenqian Yuan et al.
Food microbiology, 30(2), 448-452 (2012-03-01)
The aim of the present study was to determine the survival of Salmonella Typhimurium adapted with sodium lactate (NaL), potassium lactate/sodium acetate mixture (KL/NaA) or sodium acetate (NaA) in simulated gastric fluid (SGF) and during heat treatment. NaL-, KL/NaA- and
HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes.
Emmi Helle et al.
Frontiers in cell and developmental biology, 9, 715093-715093 (2021-08-24)
Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic development of cardiac endothelial cells and cardiomyocyte and endothelial
Articles
Mouse embryo media and embryo validated reagents for transgenic mouse embryo culture
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Is this product produced from Genetically Modified organisms (GMO's)?
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Hi, Could you tell me what is the concentration of the solution in M (or mM) please? Thank you
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The concentration of this product changes slightly from lot to lot. A solution of precisely 60% has a molarity of 7.0 M based on a density of 1.31 g/ml and a molecular weight of 112.1. Please see the link below to review a sample Certificate of Analysis:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/L7900-100ML0000229622.pdfHelpful?
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