M9281
3-Methyladenine
autophagy inhibitor
Synonym(s):
3-MA, 6-Amino-3-methylpurine
About This Item
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biological source
synthetic (organic)
Quality Level
Assay
≥99% (HPLC)
form
powder
mp
~300 °C (dec.) (lit.)
solubility
DMF: 9.80-10.20 mg/mL, clear, colorless to light yellow
SMILES string
Cn1cnc(N)c2ncnc12
InChI
1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChI key
FSASIHFSFGAIJM-UHFFFAOYSA-N
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Related Categories
Application
- to determine the expressions of autophagy-related genes (Beclin 1, light chain 3 (LC3) and p62) using the transfected human bone marrow mesenchymal stem cells (BM-MSCs)
- with cisplatin to study the inhibition of autophagy influenced cisplatin-induced apoptosis in A2780cp cells
- to study the interplay between colistin-induced autophagy and apoptosis
Biochem/physiol Actions
Preparation Note
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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