Merck
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P3932

Sigma-Aldrich

Poly(2-hydroxyethyl methacrylate)

BioReagent, powder, suitable for cell culture

Synonym(s):
Poly(2-HEMA), Poly-HEMA
Linear Formula:
(C6H10O3)n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

biological source

synthetic (organic)

product line

BioReagent

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

ethanol: 120 mg/mL

density

1.15 g/mL at 25 °C (lit.)

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Application

Poly(2-hydroxyethyl methacrylate) has been used:
  • as a nonadhesive substrate in the preparation of single cell suspensions
  • to implant into mice cornea for corneal micropocket assay
  • to coat the well plates for sphere assay using adipose-derived mesenchymal stem cells

Packaging

10, 25 g in poly bottle

Biochem/physiol Actions

Poly(2-hydroxyethyl methacrylate) is an acrylic compound and has dental usage. It is mainly used to inhibit cell adhesion to growth surfaces in culture vessels.

Physical form

Water-swellable polymer. Hydrogel.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Embryoid body formation from embryonic and induced pluripotent stem cells: Benefits of bioreactors
Rungarunlert S, et al.
World journal of stem cells, 1(1), 11-11 (2009)
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
Ignatova Tatyana N, et al.
Glia, 39(3), 193-206 (2002)
VAP-1-Mediated M2 Macrophage Infiltration Underlies IL-1beta-but Not VEGF-A-Induced Lymph-and Angiogenesis
Nakao S, et al.
The American Journal of Pathology, 178(4), 1913-1921 (2011)
Handbook of Occupational Dermatology, 564-564 (2013)
Manuele Giuseppe Muraro et al.
Stem cells translational medicine, 1(8), 592-603 (2012-12-01)
Increasing evidence that cancers originate from small populations of so-called cancer stem cells (CSCs), capable of surviving conventional chemotherapies and regenerating the original tumor, urges the development of novel CSC-targeted treatments. Screening of new anticancer compounds is conventionally conducted on

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