PZ0401

PF-06855800 variable hydrate

≥98% (HPLC)

• Synonym(s): (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol, 7-[(5R)-5-C-(4-Chloro-3-fluorophenyl)-ß-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Empirical Formula (Hill Notation): C₁₇H₁₆ClFN₄O₄ · xH₂O
• Molecular Weight: 394.78 (anhydrous basis)

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• manufacturer/tradename: Pfizer^®
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• originator: Pfizer
• storage temp.: 2-8°C

Description

Packaging

5, 25 mg

Biochem/physiol Actions

PF-06855800 is a cell penetrant, potent and selective S-adenosylmethionine (SAM) competitive inhibitor of the protein arginine methyltransferase 5 (PRMT5) that exhibits anticancer activity in both in vitro and in vivo models.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable