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SAB3500765

Sigma-Aldrich

Anti-TLR4 antibody produced in rabbit

affinity isolated antibody

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NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

mol wt

92 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TLR4(7099)

General description

Toll-like receptor 4 (TLR4) belongs to the interleukin-1 receptor (IL-1R) family. It is highly polymorphic and is located on human chromosome 9q33.1.

Immunogen

Antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TLR4.

Biochem/physiol Actions

Toll-like receptor 4 (TLR4) acts as the receptor for LPS (lipopolysaccharides ), a gram-negative bacterial cell wall component. Mutations in TLR4 affects mRNA and protein expression in colorectal cancer.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500765.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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