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SAB4700232

Sigma-Aldrich

Monoclonal Anti-CD81 antibody produced in mouse

clone M38, purified immunoglobulin, buffered aqueous solution

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NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

M38, monoclonal

form

buffered aqueous solution

species reactivity

rabbit, human, feline

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CD81(975)

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This Item
SAB4700936WH0000975M1C7423
conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody form

-

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

clone

M38, monoclonal

clone

M38, monoclonal

clone

2B7, monoclonal

clone

UCHT-4, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

rabbit, human, feline

species reactivity

rabbit, cat, human

species reactivity

human

species reactivity

human

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General description

Cluster of differentiation 81 (CD81) is expressed on the oocyte surface. It consists of five large helical segments and belongs to the tetraspanin family. The gene encoding this protein is localized on human chromosome 11p15.5.
The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Immunogen

MOLT-4 (human T-ALL cell line)

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

Cluster of differentiation 81 (CD81) has a role in membrane organization, cell-cell interactions, cellular fusion and protein trafficking. It is also involved in receptor clustering and signaling. CD81 is overexpressed in cancers.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A role for CD81 and hepatitis C virus in hepatoma mobility.
Viruses, 6, 1454-1472 (2014)
Oligomerization of the Tetraspanin CD81 via the Flexibility of Its ?-Loop.
Schmidt TH
Biophysical Journal, 110, 2463-2474 (2016)
CD81 as a tumor target.
Vences-Catalan F
Biochemical Society Transactions, 45, 531-535 (2017)
A microarray-based DNA methylation study of glioblastoma multiforme
Martinez R
Epigenetics, 4, 255-264 (2009)

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