Merck
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Sigma-Aldrich

Sigmacote®

siliconizing reagent for glass and other surfaces

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NACRES:
NA.47

biological source

synthetic

Quality Level

color

colorless

density

0.68 g/cm3

application(s)

hematology
histology

storage temp.

2-8°C

General description

Sigmacote® is a solution of a chlorinated organopolysiloxane in heptane that readily forms a covalent, microscopically thin film on glass. The film repels water, retards the clotting of blood or plasma, and prevents surface adsorption of many basic proteins. Ready to use without dilution; reusable if kept free of moisture.

Application

Sigmacote® has been used to prevent adhesion of the growth factors to plasticware. It has also been used to coat coverslip in order to prevent the adhesion of larval brain during squashing.

Biochem/physiol Actions

Sigmacote® is ideal for glass, ceramics and fiber optics. It is used to treat GC injection glass inserts.

Legal Information

Sigmacote is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Signal Word

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

24.8 °F - closed cup

Flash Point(C)

-4 °C - closed cup


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Analysis of protein S-acylation by gas chromatography-coupled mass spectrometry using purified proteins
Sorek, Nadav and Yalovsky, Shaul
Nature Protocols, 5(5), 834-834 (2010)
Comparative analysis of satellite DNA in the Drosophila melanogaster species complex
Jagannathan M, et al.
G3 (Bethesda, Md.), g3-116 (2016)
Isolation of adult stem cells and their differentiation to Schwann cells
Progenitor Cells, 47-57 (2012)

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