- SML2018
All Photos(1)
SML2018
GSK4027
≥98% (HPLC)
All Photos(1)
Synonym(s):
4-Bromo-2-methyl-5-(((3R,5R)-1-methyl-5-phenylpiperidin-3-yl)-amino)pyridazin-3(2H)-one, 4-Bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-3(2H)-pyridazinone
Empirical Formula (Hill Notation):
C17H21BrN4O
CAS Number:
Molecular Weight:
377.28
Recommended Products
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CN(C[C@H](C1)C2=CC=CC=C2)C[C@@H]1NC(C=NN(C3=O)C)=C3Br
Related Categories
Compare Similar Items
View Full Comparison1 of 4
This Item | SML0428 | SML0428 | SML2376 |
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| color white to beige | color white to beige | color white to beige | color white to beige |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 5 mg/mL (clear solution) | solubility DMSO: 5 mg/mL (clear solution) | solubility DMSO: 2 mg/mL, clear |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
Biochem/physiol Actions
GSK4027 is a cell penetrant, potent and selective inhibitor of PCAF/GCN5 bromodomain [p300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) bromodomain].
It acts as a chemical probe for PCAF/GCN5.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificate of Analysis
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Certificate of Origin
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