Size exclusion chromatography (SEC) is widely used in purification of native or recombinant proteins, viruses, and plasma-derived biotherapeutics. This separation method is not restricted by buffer composition.
Our SEC resin offerings include:
Fractogel® EMD BioSEC resin for efficient separation of dimers, high molecular weight aggregates, purification of viruses, and polishing of blood plasma factors.
Our broad portfolio of buffer materials manufactured according to GMP guidelines includes excipients specifically for drug formulation and manufacturing, including high-risk applications. Whether your product is a small or large molecule drug, we offer high-quality buffers and pH adjusters with regulatory support.
Affinity chromatography is often used during the capture phase to isolate the target molecule and reduce process volume. Our range of affinity resins includes Protein A, anti-A and anti-B, and metal chelate resin, designed for high throughput and cost-effective purification.
Membrane chromatography is a highly productive downstream purification technology used for capture through polishing. Natrix chromatography membrane is a single-use solution which improves process economics and facility utilization when compared to traditional membrane adsorbers.
Chromatography columns are critical to the successful separation of your valuable molecules. We provide columns from lab scale to pilot and process scale. From screening to large-scale production, our columns provide robust and consistent performance with the processing flexibility you need.
Single-use and multi-use chromatography systems are critical for the separation of your valuable molecules. We provide standard and custom systems from pilot to process-scale, offering robust and consistent performance with the processing flexibility you need.
Ion exchange (IEX) chromatography separates biomolecules based on difference in charge between the target molecule and chromatography resin. Widely used in bioprocessing, our anion and cation exchange chromatography resins efficiently purify mAbs, recombinant proteins, vaccines, plasma, and other therapeutic molecules.
High-performance liquid chromatography (HPLC) is a crucial step in the separation and purification of complex biomolecules. Our broad portfolio of normal-phase and reverse-phase silica gel resins economically delivers the excellent separation and high purity you need.
Consistent, reliable performance is key to blood plasma fractionation, posing challenges to improve yield, maintain process economics, and manage regulatory requirements. Learn how the right partner can help fractionators to better serve patients globally with enhanced IgG, albumin, and Factor VIII products.