ekko™ Acoustic Cell Processing System

The ekko™ cell processing system is a true fit-for-purpose cell therapy manufacturing solution, employing acoustic technology and a multi-use platform to simplify cell therapy manufacturing. Its modular design improves flexibility and utilization while imparting minimal energy and stress for gentle handling of cells.

Concentration and wash

Whether you need to process an apheresis product or are harvesting from a bioreactor, the ekko™ system processes continuously without interruption. Flexible control allows for a wide range of inputs, final concentrations, yields, and processing times. This provides peace of mind, knowing that cell viability is maintained due to low-energy acoustic forces.

A variety of cell types can be processed, including:

  • Apheresis material
  • T-cells
  • Mesenchymal stem cells (MSCs)
  • Pluripotent stem cells (PSCs)
  • Keratinocytes
  • Platelets
  • Fibroblasts
Table 1.T-Cell Harvest System Capabilities and Exemplar Results

Aggregate processing

The ekko™ system can be connected to your bioreactor of choice to enable a closed, integrated, and automated solution for your PSC aggregate expansion or differentiation process. The system is tunable to maximize single-cell removal or aggregate retention at each step, while gently minimizing cell residence time out of your bioreactor. Multiple unit operations can be performed, such as:

  • Efficient media exchanges
  • Gentle aggregate harvest
  • Harvest of single cells
  • Perfusion without need for filters
Table 2.Aggregate Pluripotent Stem Cell Media Exchange System Capabilities and Exemplar Results