Polymer synthesis

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Nanoclays in Multi-Functional Composites

Nanoclays are clay minerals optimized for use in clay nanocomposites– multi-functional material systems with several property enhancements targeted for a particular application.

The Progress in Development of Dental Restorative Materials

With dentists placing nearly 100 million dental fillings into patients′ teeth annually in the U.S. alone, polymeric composite restoratives account for a very large share of the biomaterials market.

Segmented Copolymers of p-dioxanone, Glycolide, and Lactide: Advantages and Applications in Biomedical

Main features of p-dioxanone, glycolide and lactide based copolymers

RAFT: Choosing the Right Agent to Achieve Controlled Polymerization

Find reversible addition–fragmentation chain transfer(RAFT) polymerization process, classes of RAFT agents & applications.

What Are Biomaterials?

Biocompatible / Biodegradable Polymer Tutorial

MALDI-TOF Characterization of Functionalized Polymers

MALDI-TOF MS is a tool for confirming end group identity & transformations, verifying successful & complete conjugation. Functionalized polymers enable a quick & efficient route for synthesis of various polymer conjugates for many applications if apt end group is present.

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

Designing Temperature and pH Sensitive NIPAM Based Polymers

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Chemistry at Surfaces with Self-Assembled Monolayers and SAMDI-ToF Mass Spectrometry

Introduction of Terminal Azide and Alkyne Functionalities in Polymers

Click chemistry, and the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) in particular, is a powerful new synthetic tool in polymer chemistry and material science.

High-Purity Monomers & Polymers for Ophthalmic Applications

We offer a continuously expanding selection of high-purity monomers and polymers for ophthalmic applications, along with a full range of initiators, crosslinkers, dyes, and solvents.

Functional RAFT Polymers for Biomedical Applications

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Block copolymer synthesis using a commercially available nitroxide-mediated radical polymerization (NMP) initiator

Functional Polymers for Biomedical Apps

Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Micro Review of RAFT Polymerization

Micro review of reversible addition/fragmentation chain transfer (RAFT) polymerization.

Nano Minerals: Nanoclays

Nanoclays like montmorillonite and bentonite are used in polymer-clay nanocomposites, rheology modifiers, and drug delivery carriers.

Fluorinated Hyperbranched Polymers

Fluorocarbon polymers exhibit increased thermal stability, hydrophobicity, lipophobicity, and chemical resistance compared to hydrocarbon analogs.

Materials for High and Low Refractive Index Coatings

Polymeric materials, with unique refractive index properties, find applications in photonics and optical coatings for various devices.

Initiator/Stabilizer FAQs

An article regarding common FAQs for initiators and stabilizers.

Polymer Analysis in Materials Science

Scientists at Sigma-Aldrich® routinely determine number-average molecular weight (Mn) by 1H NMR end-group analysis for polymers having Mn values under 3,000.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

RAFT Agents for Functionalized Polymers

Low-cost, high-purity RAFT Agents are vital for industrial RAFT polymerization. We supply effective agents for this technology.

Asymmetric Polymerization in Chiral Liquid Crystals

Chiral nematic liquid crystal (N*-LC) facilitates asymmetric acetylene polymerization, yielding helical chains and fibrils in polyacetylene film.

Molecular Layer Deposition of Polymers

Atomic layer deposition meets various needs including semiconductor device miniaturization and nanoparticle coating.

Functional Biomaterials Synthesized by Double-Head Polymerization Agents

Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.

Innovative Materials for Glass Ionomer Cements (GICs): Dental Applications

Innovation in dental restorative materials is driven by the need for biocompatible and natural-appearing restoration alternatives. Conventional dental materials like amalgam and composite resins have inherent disadvantages.

Chemistry in (Bio)Materials Science

"Click" Chemistry in (Bio)Materials Science

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

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