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phr1088
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Mark A Turner et al.
Archives of disease in childhood, 97(6), 573-577 (2011-06-24)
Chronic lung disease of prematurity (CLD) remains a major cause of morbidity and mortality in preterm infants. Ureaplasma has received intermittent attention over the last two decades as a possible contributory factor. In addition, pulmonary inflammation is associated with the
Francisco Wilker Mustafa Gomes Muniz et al.
European journal of pharmacology, 705(1-3), 135-139 (2013-03-19)
In most patients periodontitis is successfully treated by scaling and root planing, but some studies have shown that certain sites continue to show periodontal tissue destruction despite conventional periodontal therapy. To solve this problem, antibiotics may be administered as an
Oral azithromycin for the treatment of meibomitis.
Jonathan B Greene et al.
JAMA ophthalmology, 132(1), 121-122 (2013-11-10)
Effect of azithromycin on anticoagulation-related outcomes in geriatric patients receiving warfarin.
Kari A Mergenhagen et al.
Clinical therapeutics, 35(4), 425-430 (2013-03-05)
Warfarin is known to have multiple pharmacokinetic and pharmacodynamic interactions. Of the macrolide family, erythromycin and clarithromycin have been shown to interact with warfarin, leading to an elevated international normalized ratio (INR). The incidence of overanticoagulation in patients prescribed azithromycin
Rosacea fulminans in pregnancy: successful treatment with azithromycin.
V Fuentelsaz et al.
Clinical and experimental dermatology, 36(6), 674-676 (2011-07-01)
Zheng Gang Bai et al.
The Cochrane database of systematic reviews, 6(6), CD007270-CD007270 (2012-06-15)
Syphilis is a complex systemic disease caused by a spirochete, Treponema pallidum. The World Health Organization estimates that at least 12 million people worldwide are currently infected with syphilis. In this review we compared two current standards of treatment for
Mariann Arvai et al.
Orvosi hetilap, 154(21), 834-837 (2013-05-23)
Gonococcal conjunctivitis is a rare infection induced by Neisseria gonorrhoeae and it usually manifests as a hyperacute purulent conjunctivitis. Ocular access of the infectious secretion during sexual intercourse is the way of transmission among adults. Inclusion conjunctivitis caused by the
Barbara Snapp et al.
Advances in neonatal care : official journal of the National Association of Neonatal Nurses, 13(2), 103-107 (2013-03-28)
Bordetella pertussis is a highly contagious bacterial disease currently on the rise in the United States. The most vulnerable age group is infants younger than 1 year old. The reasons for the current outbreak are multifactorial. The following is a
Sabarinath Venniyil Radhakrishnan et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(1), 30-38 (2014-12-03)
Noninfectious lung injury and acute graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (allo-HCT) are associated with significant morbidity and mortality. Azithromycin is widely used in allogeneic HCT recipients for pulmonary chronic GVHD, although current data appear controversial. We induced
Kai-Hua Chi et al.
The American journal of tropical medicine and hygiene, 92(1), 134-138 (2014-11-19)
We developed a TaqMan-based real-time quadriplex polymerase chain reaction (PCR) to simultaneously detect Treponema pallidum subspecies pallidum, T. pallidum subsp. pertenue, and T. pallidum subsp. endemicum, the causative agents of venereal syphilis, yaws, and bejel, respectively. The PCR assay was
Macrolide antibiotics for prevention of chronic obstructive pulmonary disease exacerbations: are we there yet?
Marcos I Restrepo et al.
American journal of respiratory and critical care medicine, 190(1), 1-2 (2014-07-02)
The impact of azithromycin therapy on the airway microbiota in asthma.
Mariel Slater et al.
Thorax, 69(7), 673-674 (2013-11-30)
Anna M van Eijk et al.
The Cochrane database of systematic reviews, (2)(2), CD006688-CD006688 (2011-02-18)
To prevent the development of drug resistance, the World Health Organization (WHO) recommends treating malaria with combination therapy. Azithromycin, an antibiotic with antimalarial properties, may be a useful additional option for antimalarial therapy. To compare the use of azithromycin alone
Azithromycin for elderly patients with pneumonia.
Aref A Bin Abdulhak et al.
JAMA, 312(13), 1352-1352 (2014-10-01)
Macrolides and bronchiectasis: clinical benefit with a resistance price.
J Stuart Elborn et al.
JAMA, 309(12), 1295-1296 (2013-03-28)
Meron Haile et al.
The American journal of tropical medicine and hygiene, 89(4), 717-720 (2013-09-05)
Latrine use has been promoted as a component of an integrated strategy for trachoma control. As part of a randomized trial in Ethiopia, 12 communities received a mass azithromycin distribution followed by a latrine promotion intervention. A random sample of
Patricia A Howard
The Annals of pharmacotherapy, 47(11), 1547-1551 (2013-11-29)
To review the possible association between azithromycin and increased cardiovascular risk. A literature search of MEDLINE (1946-August 2013) was performed using the search terms macrolide, azithromycin, QT prolongation, cardiovascular, and torsade de pointes. Additional references were identified from a review
LC determination of impurities in azithromycin tablets
Miguel L and Barbas C
Journal of Pharmaceutical and Biomedical Analysis, 33(2), 211-217 (2003)
Patrick Horner et al.
Current opinion in infectious diseases, 27(1), 68-74 (2013-12-11)
Mycoplasma genitalium is a sexually transmitted infection that causes significant morbidity in men and women and is a co-factor in HIV transmission. However, commercial diagnostic tests are not generally available for M. genitalium and sub-optimal treatment is often given. We
M Bartelsman et al.
Sexually transmitted infections, 90(5), 358-362 (2014-05-27)
To compare point-of-care (POC) systems in two different periods: (1) before 2010 when all high-risk patients were offered POC management for urogenital gonorrhoea by Gram stain examination; and (2) after 2010 when only those with symptoms were offered Gram stain
Josje Altenburg et al.
JAMA, 309(12), 1251-1259 (2013-03-28)
Macrolide antibiotics have been shown beneficial in cystic fibrosis (CF) and diffuse panbronchiolitis, and earlier findings also suggest a benefit in non-CF bronchiectasis. To determine the efficacy of macrolide maintenance treatment for adults with non-CF bronchiectasis. The BAT (Bronchiectasis and
Sonja Gandhi et al.
JAMA, 310(23), 2544-2553 (2013-12-19)
Calcium-channel blockers are metabolized by the cytochrome P450 3A4 (CYP3A4; EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels when CYP3A4 activity is inhibited. Clarithromycin is an inhibitor of CYP3A4 and azithromycin is not, which makes
Karly P Garnock-Jones
Drugs, 72(3), 361-373 (2012-02-10)
The second-generation macrolide azithromycin is available as a 1.5% ophthalmic solution for use in the treatment of bacterial or trachomatous conjunctivitis. This article reviews the pharmacological properties of azithromycin 1.5% ophthalmic solution and its clinical efficacy and tolerability in patients
Sima Rassai et al.
International journal of clinical pharmacology and therapeutics, 51(6), 490-494 (2013-04-04)
Different immunologic mechanisms contribute to development of inflammation in acne vulgaris and immunologic effect of levamisole has been demonstrated. The aim of this study was to compare azithromycin and levamisole with azithromycin alone in the treatment of acne vulgaris. An
Jamshid Vafaeimanesh et al.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 25(1), 53-57 (2014-01-18)
To compare a triple-therapy regimen based on change of antibiotic (azithromycin and clarithromycin) for the eradication of Helicobacter pylori in hemodialysis (HD) patients, we studied in a prospective, randomized, double-blinded clinical trial 39 patients who had dyspepsia and showed two
Treatment of gonococcal infection: when one drug is not enough.
Lisa N Kransdorf et al.
Journal of women's health (2002), 23(7), 627-628 (2014-06-12)
Sidharath D Thakur et al.
Sexually transmitted infections, 90(4), 297-302 (2014-02-08)
To investigate the molecular epidemiology of isolates of Neisseria gonorrhoeae from Saskatchewan, Canada, using Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), and to assess associations between antimicrobial susceptibility (AMS) and specific strain types (STs). 320 consecutive gonococcal isolates, collected between
Aimee K Murray et al.
Environmental health perspectives, 128(10), 107007-107007 (2020-10-22)
Antimicrobial resistance (AMR) is one of the most significant health threats to society. A growing body of research demonstrates selection for AMR likely occurs at environmental concentrations of antibiotics. However, no standardized experimental approaches for determining selective concentrations of antimicrobials
R Siekmeier et al.
Advances in experimental medicine and biology, 839, 13-24 (2014-09-26)
Systemic antibiotic treatment is established for many pulmonary diseases, e.g., cystic fibrosis (CF), bronchiectasis and chronic obstructive pulmonary disease (COPD) where recurrent bacterial infections cause a progressive decline in lung function. In the last decades inhalative administration of antibiotics was
Determination of erythromycin, clarithromycin, roxithromycin, and azithromycin in plasma by high-performance liquid chromatography with amperometric detection
Taninaka C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 738(2), 405-411 (2000)
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