Merck

Sulfation made simple: a strategy for synthesising sulfated molecules.

Chemical communications (Cambridge, England) (2019-03-19)
Daniel M Gill, Louise Male, Alan M Jones
ABSTRACT

The study of organosulfates is a burgeoning area in biology, yet there are significant challenges with their synthesis. We report the development of a tributylsulfoammonium betaine as a high yielding route to organosulfates. The optimised reaction conditions were interrogated with a diverse range of alcohols, including natural products and amino acids.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
TBSAB, ≥95%