The Proligo® manufacturing site in Hamburg, Germany is designed as a multi-purpose facility with built-in flexibility and the capability to manufacture a complex mix of products to suit a variety of customer needs.
DNA and RNA phosphoramidites are manufactured in glass-lined reactors and purified by preparative column chromatography on silica gel with medium-to-high pressure chromatography equipment.
The Hamburg facility has the flexibility to prepare and purify alternative mixes of high volume standard products as well as small-scale specialties.
Proligo offers reagents for the synthesis of oligonucleotides including phosphoramidites, solid supports and liquid formulations.
Annual amidite production capacity is more than five tons, to meet growing industry demands and ensure reliable supply.
Large-scale production facilities include:
Research. Development. Production.
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