P5280

Sodium pyruvate

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

• Synonym(s): α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
• Linear Formula: CH₃COCOONa
• CAS Number: 113-24-6
• Molecular Weight: 110.04
• Beilstein: 3568341
• EC Number: 204-024-4
• MDL number: MFCD00002586
• PubChem Substance ID: 24898615
• NACRES: NA.71

Properties

• product line: BioReagent
• Quality Level: 200
• assay: ≥99%
• form: powder
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• mp: >300 °C (lit.)
• solubility: H₂O: 100 mg/mL
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(=O)C([O-])=O
• InChI: 1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• InChI key: DAEPDZWVDSPTHF-UHFFFAOYSA-M

Description

General description

Pyruvate is the anion of pyruvic acid.

Application

Sodium pyruvate has been used:

• to culture MCF7 ρ0 (human breast cancer cell line) cells as parent cells
• as a supplement in extracellular flux (XF) assay media to incubate cells for measuring oxygen consumption rate (OCR)
• as a supplement in minimum essential medium Eagle to maintain breast cancer (MCF-7) cells
• as a supplement in Dulbecco′s modified Eagle medium (DMEM)-based medium and modified Eagle medium (MEM)-α for testis cell culture to evaluate the effect of medium composition on in vitro SSC maintenance

Packaging

25, 100, 500 g in poly bottle

Biochem/physiol Actions

Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Sodium pyruvate can be used as a component in culture broth and media. It exhibits protective effects in various animal models of ischemia-reperfusion injury, hemorrhagic shock, and septic shock when given exogenously.

Features and Benefits

• Cell culture and insect cell culture tested

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317 - H319
• Precautionary Statements: P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1B
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves