L4646

Lipids Cholesterol Rich from adult bovine serum

liquid, sterile-filtered, BioReagent, suitable for cell culture, suitable for insect cell culture

• NACRES: NA.75

Properties

• sterility: sterile-filtered
• Quality Level: 200
• product line: BioReagent
• form: liquid
• composition: Cholesterol, 9.0-11.0 g/L ; Protein, 15.0-25.0 g/L
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• impurities: Adventitious viral agents, none detected (9 CFR; 113.53); IgG, none detected (RID); Microbial content, none detected (USP XXII); Mycoplasma, none detected (Barile method); ≤6.0 EU/mg cholesterol endotoxin
• storage temp.: 2-8°C

Description

General description

Cholesterol is a lipid molecule, found integrated to the cell membrane.

Application

Lipids Cholesterol Rich from adult bovine serum has been used as one of the lipid component to generate erythroblasts ex vivo. It has also been used as a standard to determine muscle cholesterol level, spectrophotometrically.

Biochem/physiol Actions

Cholesterol significantly affects the property of phospholipid membrane such as fluidity and membrane protein function. It exhibits a condensing effect towards phospholipids. Cholesterol-phospholipid interaction influences physiological properties of a lipid bilayer. Cholesterol serves as a precursor of bile acids, steroid hormones and vitamin D. Uncontrolled level of plasma cholesterol might lead to the risk of cardiovascular disorder.

Other Notes

Aqueous lipoprotein solution

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable