Merck
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RAB0489

Sigma-Aldrich

Human soluble TNF Receptor 1 ELISA Kit

for serum, plasma, cell culture supernatants and urine

Synonym(s):
sTNFRI

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.55-400 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNFRSF1A(7132)

General description

The Human sTNF RI (soluble tumor necrosis factor receptor I) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human sTNF RI in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human TNF RI

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Tumour necrosis factor (TNF) receptor superfamily member 1A is a type I single transmembrane glycoprotein. Signal transduction mediated by binding of TNFα regulates inflammatory, immune responses and apoptotic pathway. TNF receptor 1 is implicated in the end-stage renal disease and associated mortality.[1] Mutations in TNF receptor 1 causes autosomal dominant tumor necrosis factor receptor-associated periodic syndrome (TRAPS).[2] Polymorphism in TNF receptor 1 causes multiple sclerosis.[3]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)

  • RABSTOP3ELISA Stop Solution (Item I)

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  • RABWASH420X Wash Buffer (Item B)

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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