Chemical Biology
Chemical biology products incorporate the techniques and strengths of chemistry to address fundamentally important questions in biology, medicine, and drug discovery. Sigma-Aldrich® chemical biology products provide solutions, expertise, and industry leadership to advance your research. We offer a market-leading range of innovative products for conjugation strategies, such as azide-alkyne cycloaddition chemistry, as well as synthetic intermediates and building blocks for the synthesis of biomolecules, such as peptides, carbohydrates, and oligonucleotides.
Carbohydrates
Our broad portfolio of highly pure carbohydrates are used widely as supplements to cell culture media and as building blocks in glycan and glycoconjugate synthesis.
Click Chemistry Reagents
Our portfolio of click chemistry reagents includes a variety of azides, alkynes, catalysts, and ligands to accelerate your progress in chemical biology, polymer chemistry, bioconjugation, and drug discovery.
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Our portfolio of linkers and crosslinkers provide structural stability and reliability in protein-protein, protein-peptide, and peptide/protein-small molecule interactions for all your bioconjugation needs.
Our protein degrader building blocks are the easiest way to generate libraries of protein degraders, such as proteolysis targeting chimeras (PROTAC®...
Our chemical biology tools incorporate techniques and strengths of chemistry to address fundamentally important research in biology, medicine, and drug discovery.
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Starch
soluble GR for analysis ISO
D-(+)-Glucose
anhydrous for biochemistry Reag. Ph Eur
IPTG, Dioxane-Free, High Purity
CAS 367-93-1 is used in the stimulation of β-galactosidase in cellular systems in which dioxane would disrupt normal cell function.
Sucrose
for biochem. Reag. Ph Eur
Sorbitol
A sugar alcohol produced by reduction of glucose.
Carboxymethylcellulose, Sodium Salt, Low Viscosity
Substrate for cellulase. Low viscosity (2%, H2O, 25°C): 25 - 75 mPas.
Heparin, Sodium Salt, Porcine Intestinal Mucosa
β-Glucan, Saccharomyces cerevisiae
A major structural element of the yeast cell wall having a β1,3-glucan linear structure with a small number of β1,6-glucan branches. Has been shown to induce an oxidative burst response from NR8383 cells.
Sucrose
Molecular Biology Grade
UDP-α-D-Galactose, Disodium Salt
A donor substrate for galactosyltransferases used in the biosynthesis of galactose-containing oligosaccharides. Decreased red blood cell levels of UDP-Gal are found in patients with maple syrup urine disease or phenylketonuria.
UDP-α-D-Glucose, Disodium Salt
Donor substrate for glucosyltransferases. A key intermediate in the biosynthesis of glycogen.
CMP-Sialic Acid, Disodium Salt
CMP-sialic acid is the activated form of sialic acid that is required for the biosynthesis of sialic acid-containing complex carbohydrates.
Hyaluronic Acid, Sodium Salt, Streptococcus pyrogenes
Natural high-viscosity mucopolysaccharide with alternating β1,3-glucuronidic and β1,4-glucosaminidic bonds. Principal glycosaminoglycan in connective tissue fluids.
N-Glycolylneuraminic Acid
Formed by the action of CMP-Neu5Ac hydroxylase. Humans are devoid of this compound due to a mutation in the human CMP-Neu5Ac hydroxylase gene that occurred after the Homo-Pan divergence.
2-Deoxy-D-glucose
Non-metabolizable derivative of glucose that can be carried by the glucose carrier in human erythrocytes. An indirect inhibitor of hexokinase. Reported to reduce the incidence of doxorubicin-induced apoptosis.
L(+)Arabinose
A pectin sugar widely distributed in plants, usually in the form of complex polysaccharides.
D-(+)-Glucose monohydrate
for biochemistry
Maltose monohydrate
for biochemistry
Carboxymethylcellulose, Sodium Salt, High Viscosity
Substrate for cellulase. High viscosity (2%, H2O, 25°C): 800 - 3100 mPas.
D(-)Mannitol
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