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ProClin™ Preservatives

Proclin™ biocide preservative inhibits microbial Kreb cycle in several places

ProClin™ preservatives are water-soluble formulations of biocides that are among the most effective biocides in the IVD industry, used in over 1,000 FDA registered IVD kits from industry-leading diagnostic manufacturers. At low working concentrations, ProClin™ products help extend the shelf life of IVD reagents by effectively and immediately inhibiting a broad spectrum of microbes.

ProClin™ biocides attack the Krebs cycle at four key points: the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. Because all bacteria and fungi possess at least part of the Krebs cycle, they are broad spectrum in their activity.

Unlike other biocides, ProClin™ preservatives present reduced health hazards, toxicology problems, and disposal issues at recommended usage levels.

We offer four unique formulations, ensuring a variety of options to meet a wide range of specific needs. Learn more about our ProClin™ products.

We provide ProClin™ biocide product range with different characteristic formulations in multiple pack sizes to suit your specific needs.

Additionally, we also provide ProClin™ support products like a ProClin™ reference standard and a ProClin™ variety kit, useful in testing and evaluating the use of ProClin™ within a specific diagnostic reagent or assay.




Despite the enhanced safety profile of ProClin™ products, a study from an independent lab has shown equivalent or improved efficacy when compared to top alternatives like thimerosal and sodium azide.

ProClin™ preservatives are readily available in convenient pack sizes suitable for all manufacturing processes and volumes. The ProClin™ Variety Kit (48119-U ) contains 5 mL bottles of all four formulations and is an excellent tool to evaluate the suitability of ProClin™ products for their specific applications. Want to see how ProClin™ biocides benefit your reagent? Request a sample.

ProClin™ preservatives are restricted to use in IVD assay development. Contact your local regulatory body for specific biocide usage and handling guidelines.