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Fibronectin
Fibronectin (FN) is a multifunctional, extracellular plasma glycoprotein produced by hepatocytes that circulates at near micromolar concentration and assembles into extracellular matrix fibrils at cell surfaces along with locally produced cellular FN.
dECM hydrogels 3D culture
Comparison of decellularized extracellular matrix (dECM) hydrogels to Matrigel® matrices for predictive 3D cell culture models
High-Throughput Drug Screening using TrueGel3D® HTS Hydrogel Plates
Compound cytotoxicity screening assays with 3D cell cultures using TrueGel3D® HTS Hydrogel Plates including dose response curves, IC50 determination, and spheroid killing assay data.
3D Cell Culture with Corning Microplates
Take a deep dive into the world of 3D cell culture courtesy of Corning and understand why the Corning® spheroid microplate can be an asset in the evolution of 3D cell culture.
An ECM Mimetic Library for Engineering Surfaces to Direct Cell Surface Receptor Binding Specificity and Signaling
The extracellular (ECM) microenvironment, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions. For this reason, engineering the ECM microenvironment provides
3D Pluripotent Stem Cells: Simplified Culture and Realistic Differentiation
This white paper illustrates the importance of three-dimensional (3D) cell culture in the production of pluripotent stem cell (PSC)-derived models of embryo development and differentiation. It contains a general overview of embryoid bodies (EBs) and a comparison between the various
Utilization of TrueGel3D™ Hydrogels to Study Fibroblast Spreading
Fibroblasts that are present in the stroma secrete glycoproteins and polysaccharides to form extracellular matrix. They maintain the structural integrity within the connective tissue and play a key role in cancer, chronic obstructive pulmonary diseases, idiopathic pulmonary fibrosis, scleroderma and
Create a 3D kidney nephrotoxicity model on the AIM Biotech 3D cell culture chip
AIM Biotech’s easy-to-use modular platform for conducting 3D cell culture into your research. The AIM Biotech organ-on-a-chip enables you to run simple assays or create more complex microphysiological systems. The versatile platform is suitable for a wide variety of cell
MaxGel™ ECM Hydrogel: An In Vitro Human Cell Derived Basement Membrane Extract for 3D Cell Culture Applications
Human cell derived basement membrane extract (BME) hydrogel for 3D cell culture of primary cell, stem cell and xenograph cancer models.
3D Organoid Culture: New In Vitro Models of Development and Disease
Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.
TrueGel3D™ Hydrogel for 3D Cell Culture
TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions
Lung Cancer Organoid Biobank
Explore our cryopreserved human lung organoid biobank from NSCLC tumor biopsies for lung cancer, SARS-CoV2, COPD and pulmonary disease research. Lung organoid 3D cell culture protocol available.
Millicell® Microwell Plates Frequently Asked Questions (FAQs)
Explore answers to your frequency asked questions about Millicell® Microwell plates. Our plates support reliable organoid culture with array of ultra-dense microwells in hydrogel for immunology, drug development, and cell therapy applications.
Blood Brain Barrier Antibody Penetration Assay using Millicell® Microwell Plates
Discover a high throughput assay using organoids and Millicell® Microwell plates. Our novel blood brain barrier model allows direct cell-to-cell interactions, closely modeling the in vivo properties.
Millicell® Ultra-Low Attachment Plates Spheroid Formation Performance Comparison
Learn about the similarities and differences in spheroid formation, roundness, and circularity between Millicell® ultra-low attachment plates and other ULA plates.
HyStem™ Hyaluronic Acid Based Hydrogels for 3D Cell Culture Applications
Hystem 3D hydrogels are based on hyaluronic acid, a major component of the extracellular matrix. 3D cell culture can be done using Hystem hydrogels.
What is Hyaluronan?
Hyaluronan is a major component of the extracellular matrix. It’s the simplest glycosaminoglycan, and it plays several biological roles.
Extracellular Matrix Proteins and Tools for Cell Culture Optimization
Extracellular matrix proteins such as laminin, collagen, and fibronectin can be used as cell attachment substrates in cell culture.
ECM Gel Matrix: Protocols Using EHS Basement Membrane Extracts
Cell culture protocols using ECM Gel Matrix EHS basement membrane extract (BME) for neurite outgrowth, cell invasion and angiogenesis tube formation assays.
High-Throughput 3D Cell Culture Using TrueGel3D® HTS Hydrogel Plates
The TrueGel3D® HTS Hydrogel Plate is a ready-to-use solution to easily establish 3D cell cultures using fully synthetic hydrogels in a simple and automation-compatible manner.
Co-culture of Tumor and Stromal Cells in TrueGel3D™ Hydrogels
TrueGel3D™ synthetic hydrogel can be used to study co-culture of tumor and stromal cells.
3D Cell Culture Tools and Techniques
3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models
Three-Dimensional Bioprinting for Tissue and Disease Modeling
Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.
Webinar: Cell Culture in 3D Systems; Moving from a 2D to 3D Environment.
Cell culture in 3D systems: moving from 2D to 3D cell culture? It’s now well accepted by the scientific community that the 3D cell culture condition better recapitulate the in vivo environment and behaviours of cells.
Advanced Cell Culture Technology for Generation of In Vivo-like Tissue Models
Sophisticated models are developing as 3D cell culture technology becomes established and accepted as a means of creating more physiologically relevant cell-based assays.
3D Imaging of Optically Cleared Spheroids in Corning® Spheroid Microplates
Discover how Corning® Spheroid Microplates played a key role in the use of use of 3D cell cultures for in vitro drug discovery assay.
Cancer Stem Cell Proliferation in Human Prostate and Breast Cancer Cell Lines Utilizing a New Defined Serum-Free 3D Spheroid Media
Serum-free defined cancer stem cell media used to grow and expand cancer cells in 3D tumorsphere aggregates.
Photocrosslinkable Hydrogels for 3D Cell Culture and Tissue Engineering
Methacrylated collagen, hyaluronic acid, and gelatin (GelMA) hydrogels can be crosslinked with light and photoinitiators (Irgacure/LAP/Ruthenium), used as 3D cell culture scaffolds and bioinks for bioprinting.
Hydrogels for 3D Cell Culture
Hydrogela are the most widely used systems for 3D cell culture. Learn more about this technology (what are hydrogels? How to chose?)
Organoid Culture Frequently Asked Questions
Organoid culture FAQs. Learn how to culture and analyze organoids following established 3D cell culture protocols. Tips and tricks.
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