Accurate protein binding affinities were measured using bioSPME more rapidly than membrane dialysis (RED) techniques. Binding affinities correlated to the reference values.
SPME fibers with Carboxen®/Polydimethylsiloxane (CAR/PDMS) and Polydimethylsiloxane/ Divinylbenzene (PDMS/DVB) coatings are now available on a nitinol core (NIT) in a SS assembly for improved fiber performance.
SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.
In the flavor and fragrance industry, analytical chemists are often required to isolate key ingredients, off-flavor components, or trace organic compounds from their sample matrices without altering their structure or composition.
Bisphenol A (BPA) plastic is controversial in food and beverage containers. This study demonstrates SPME of BPA from an energy drink using an overcoated PDMS/DVB fiber, followed by GC/MS/MS analysis using SLB-PAHms GC Column.
A comparison between Carboxen®/PDMS coated nitinol core and fused silica core adsorbent SPME fibers for factors, such as coating process, testing process, inertness, raw materials, and durability.
Comparative analysis of Supel™ BioSPME 96-Pin device with a rapid equilibrium dialysis technique for accuracy of measured values, sample cleanliness, and workflow time in drug protein binding.