RUNX2
runt-related transcription factor 2
别名:
AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
物种:
Human RUNX2 (860), Mouse Runx2 (12393), Rat Runx2 (367218), Goat RUNX2 (100861217), domestic guinea pig Runx2 (100734175), cow RUNX2 (536911), chicken RUNX2 (373919), Domestic Rabbit RUNX2 (100008943), Horse RUNX2 (100033890), domestic cat RUNX2 (101089612) ...展开
UniProtKB ID:
基因ID:
- Human(860) Summary: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
- Mouse(12393) runt related transcription factor 2
- Rat(367218) runt-related transcription factor 2
- Goat(100861217) runt-related transcription factor 2
- domestic guinea pig(100734175) runt-related transcription factor 2
- cow(536911) runt-related transcription factor 2
- chicken(373919) runt-related transcription factor 2
- Domestic Rabbit(100008943) runt-related transcription factor 2
- Horse(100033890) runt-related transcription factor 2
- domestic cat(101089612) runt-related transcription factor 2
- sheep(101115489) runt-related transcription factor 2
- dog(474923) runt-related transcription factor 2
- dog(449531) runt-related transcription factor 2
- naked mole-rat(101724767) runt-related transcription factor 2
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Antibodies
产品编号
说明
物种反应性
应用
Anti-RUNX2 Antibody, clone AS110, clone AS110, from mouse,
物种反应性
human
应用
immunocytochemistry
western blot
western blot