Merck

125504

Sigma-Aldrich

环丙胺

98%

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别名:
氨基环丙烷
线性分子式:
C3H5NH2
CAS号:
分子量:
57.09
Beilstein:
741858
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

4.67 psi ( 20 °C)

质量水平

检测方案

98%

形式

liquid

自燃温度

527 °F

折射率

n20/D 1.420 (lit.)

bp

49-50 °C (lit.)

密度

0.824 g/mL at 25 °C (lit.)

SMILES string

NC1CC1

InChI

1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2

InChI key

HTJDQJBWANPRPF-UHFFFAOYSA-N

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8.18017790826PH017756
Cyclopropylamine 98%

Sigma-Aldrich

125504

环丙胺

Cyclopropylamine for synthesis

Sigma-Aldrich

8.18017

Cyclopropylamine

form

liquid

form

liquid

form

liquid

form

solid

refractive index

n20/D 1.420 (lit.)

refractive index

-

refractive index

-

refractive index

-

bp

49-50 °C (lit.)

bp

-

bp

-

bp

-

density

0.824 g/mL at 25 °C (lit.)

density

0.82 g/cm3 at 20 °C

density

-

density

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

应用

环丙胺 (CPA) 用于 N -\ [4-(4-氟)苯基-2-氨基噻唑-5-基] 嘧啶-2-基-烷基胺衍生物的合成 。已用于合成 Pt (CPA) 2 甲硫亚甲基丙二酸酯)和 Pt (CPA) 2 乙基硫亚甲基丙二酸酯)配合物

生化/生理作用

环丙胺通过一种机制使细胞色素 P450 酶失活,该机制包括在氮气中先发生单电子氧化,然后环丙烷环断裂,导致酶的共价修饰 。它是 脱氮副球菌 中一种基于机制的喹啉甲胺脱氢酶抑制剂。

配件

产品编号
说明
价格

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(F)

33.8 °F - closed cup

闪点(C)

1 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles


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其他客户在看

Slide 1 of 2

1 of 2

Dapeng Sun et al.
FEBS letters, 517(1-3), 172-174 (2002-06-14)
Cyclopropylamine is a mechanism-based inhibitor of the quinoprotein methylamine dehydrogenase (MADH) from Paracoccus denitrificans. The resulting inactivation is accompanied by the formation of a covalent cross-link between the alpha and beta subunits of MADH. The results of site-directed mutagenesis studies
Synthesis and Antifungal Activity of 5-[2-(Alkylamino) pyrimidin-4-yl]-4-phenylthiazol-2-cycloalkylamine Derivatives on Phytophthora capsici.
Nam Sw, et al.
J. Korean Chem. Soc., 54(3), 395-402 (2011)
David J Aitken et al.
Organic & biomolecular chemistry, 9(21), 7517-7524 (2011-09-23)
The Kulinkovich-de Meijere reaction between an unsaturated Grignard reagent and a chiral amide takes place with a high trans stereoselectivity and provides a convenient access to non-racemic trans cyclopropylamines. These compounds are transformed in four steps into the corresponding N-protected
Qin Sun et al.
Chemical research in toxicology, 21(3), 711-719 (2008-02-27)
Trovafloxacin (Trovan) is a fluoroquinolone antibiotic drug with a long half-life and broad-spectrum activity. Since its entry into the market in 1998, trovafloxacin has been associated with numerous cases of hepatotoxicity, which has limited its clinical usefulness. Trovafloxacin possesses two
Mark E Scott et al.
The Journal of organic chemistry, 73(21), 8154-8162 (2008-10-10)
This manuscript describes a highly selective iodide-mediated, tandem Mannich/cyclization to afford trans-2,3-disubstituted pyrrolidines from methylenecyclopropyl amides in good to excellent yields and selectivities. The reaction scope has been drastically expanded to include a wide array of aromatic, heteroaromatic and alpha,beta-unsaturated

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