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质量水平
方案
97%
表单
solid
沸点
208 °C/25 mmHg (lit.)
mp
55-57 °C (lit.)
官能团
ketone
phenyl
SMILES字符串
[H]\C(=C(\[H])C(=O)c1ccccc1)c2ccccc2
InChI
1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
InChI key
DQFBYFPFKXHELB-VAWYXSNFSA-N
基因信息
human ... IL1B(3553)
rat ... Ar(24208)
一般描述
反式 -查尔酮是一种开链类黄酮,可能预防肺癌和前胃癌。
应用
反式-查尔酮用于合成cis和反式二苯基环丙烷。 它还用于筛选异丁基苯和 4-异丁基苯乙酮的表面吸附物质,用于散装的 Fsfotungstic Wells-Dawson 酸 (H6P2W18O62.xH2O)。
生化/生理作用
反式-查耳酮具有抗红霉素的抗真菌活性。它是脂肪酸合成酶和α-淀粉酶的抑制剂。由于拟南芥根中线粒体跨膜电位降低,它可诱导程序性细胞死亡。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Franco Chimenti et al.
Journal of medicinal chemistry, 52(9), 2818-2824 (2009-04-22)
A large series of substituted chalcones have been synthesized and tested in vitro for their ability to inhibit human monoamine oxidases A and B (hMAO-A and hMAO-B). While all the compounds showed hMAO-B selective activity in the micro- and nanomolar
P M Sivakumar et al.
Bioorganic & medicinal chemistry letters, 17(6), 1695-1700 (2007-02-06)
In order to develop relatively small molecules as antimycobacterial agents, twenty-five chalcones were synthesized, their activity was evaluated, and quantitative structure-activity relationship (QSAR) was developed. The synthesis was based on the Claisen-Schimdt scheme and the resultant compounds were tested for
Surface intermediate species of the 4-isobutylacetophenone adsorption-reaction over fosfotungstic Wells-Dawson heteropoly acid.
Matkovic SR, et al.
Latin American Applied Research, 39(2), 173-178 (2009)
Carla Díaz-Tielas et al.
Plant, cell & environment, 35(8), 1500-1517 (2012-03-21)
Chalcone (1,3-diphenyl-2-propen-1-one) is an aromatic ketone precursor of important molecules in plants such as flavonoids or anthocyanins. Its phytotoxicity has been demonstrated on different plant species, but to date little is known about the mechanisms of action of this secondary
Asymmetric induction with β-cyclodextrin: cis-trans photoisomerization of diphenyl-cyclopropane and its derivatives.
Koodanjeri S, et al.
Proceedings of the Indian Academy of Sciences - Section A, 68(5), 453-463 (2002)
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