Merck
All Photos(3)

157945

Sigma-Aldrich

(4-羧丁基)三苯基溴化膦

98%

Synonym(s):
5-(Triphenylphosphonio)pentanoic acid bromide, Carboxybutyltriphenylphosphonium bromide, NSC 147756
Linear Formula:
(C6H5)3P(Br)(CH2)4COOH
CAS Number:
Molecular Weight:
443.31
Beilstein:
3586477
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

200

测定

98%

形式

powder

reaction suitability

reaction type: C-C Bond Formation

mp

204-207 °C (lit.)

SMILES string

[Br-].OC(=O)CCCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C23H23O2P.BrH/c24-23(25)18-10-11-19-26(20-12-4-1-5-13-20,21-14-6-2-7-15-21)22-16-8-3-9-17-22;/h1-9,12-17H,10-11,18-19H2;1H

InChI key

MLOSJPZSZWUDSK-UHFFFAOYSA-N

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应用

  • 用作促凋亡肽递送至肿瘤细胞线粒体的平台

制备用反应物:
  • 通过关环置换和双键迁移关环置换反应得到的环骨架
  • 甲基烯基喹诺酮类抗分枝杆菌药物
  • 通过金催化 Meyer-Schuster 重排的前列腺素及其药物类似物
  • 二苯基甲基哌嗪作为 N 型钙通道阻滞剂作为潜在的治疗药物
  • 具有抗肿瘤活性的叶酸受体特异性甘氨酰胺核糖核苷酸甲酰基转移酶 (GARFTase) 抑制剂
  • 通过 Wittig 反应测定具有抗利什曼病活性的环烷基烷醇

包装

50, 250 g in poly bottle

象形图

CorrosionSkull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Eye Dam. 1

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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