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202487

Sigma-Aldrich

聚乙二醇甲基醚

average MN 550, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

线性分子式:
CH3(OCH2CH2)nOH
CAS号:
9004-74-4
MDL號碼:
MFCD00084416
分類程式碼代碼:
12162002
PubChem物質ID:
24852066
NACRES:
NA.23

产品名称

聚乙二醇甲基醚, average Mn 550

蒸汽密度

>1 (vs air)

品質等級

200

蒸汽壓力

0.05 mmHg ( 20 °C)

形狀

semisolid

分子量

average Mn 550

折射率

n20/D 1.455

黏度

7.5 cSt(210 °F)(lit.)

轉變溫度

Tm 20 °C

密度

1.089 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

SMILES 字串

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI 密鑰

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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應用

聚（乙二醇）甲基醚可作为成孔剂， 以制备亲水性增强的聚砜膜。

聚（乙二醇）甲基醚接枝的聚酰胺 （PAMAM）树枝状聚合物可作为抗癌药物的 载药体系。

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

359.6 °F - closed cup

閃點（°C）

182 °C - closed cup

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分析证书(COA)

Lot/Batch Number
0000377733
0000319951
0000319951
0000377733
0000249498

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聚乙二醇二甲醚500 (stabilised) for synthesis

Sigma-Aldrich

8.14171

聚乙二醇二甲醚500

Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Junhwa Shin et al.
Molecular pharmaceutics, 9(11), 3266-3276 (2012-10-04)
A family of 3-methoxypoly(ethylene glycol)-vinyl ether-1,2-dioleylglycerol (mPEG-VE-DOG) lipopolymer conjugates, designed on the basis of DFT calculations to possess a wide range of proton affinities, was synthesized and tested for their hydrolysis kinetics in neutral and acidic buffers. Extruded ∼100 nm
Oliver J Harrison et al.
Cell reports, 30(8), 2655-2671 (2020-02-27)
Non-clustered δ1- and δ2-protocadherins, close relatives of clustered protocadherins, function in cell adhesion and motility and play essential roles in neural patterning. To understand the molecular interactions underlying these functions, we used solution biophysics to characterize binding of δ1- and
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
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