Merck

202487

Sigma-Aldrich

聚乙二醇甲基醚

average Mn 550

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别名:
mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚
线性分子式:
CH3(OCH2CH2)nOH
CAS号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.23

蒸汽密度

>1 (vs air)

质量水平

蒸汽压

0.05 mmHg ( 20 °C)

形式

semisolid

分子量

average Mn 550

折射率

n20/D 1.455

粘度

7.5 cSt(210 °F)(lit.)

转变温度

Tm 20 °C

密度

1.089 g/mL at 25 °C

Ω端

hydroxyl

α端

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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8132371578732621
Poly(ethylene glycol) methyl ether average Mn 550

Sigma-Aldrich

202487

聚乙二醇甲基醚

-
Poly(ethylene glycol) methyl ether average Mn 5,000

Sigma-Aldrich

81323

聚乙二醇甲基醚

-
Poly(ethylene glycol) methyl ether BioUltra, 500

Sigma-Aldrich

71578

聚乙二醇甲基醚

Premium Grade
Poly(ethylene glycol) methyl ether average Mn 10,000

Sigma-Aldrich

732621

聚乙二醇甲基醚

-
mol wt

average Mn 550

mol wt

average Mn 5,000

mol wt

470-530

mol wt

average Mn 10,000

transition temp

Tm 20 °C

transition temp

-

transition temp

-

transition temp

-

density

1.089 g/mL at 25 °C

density

-

density

-

density

-

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

-

Ω-end

hydroxyl

α-end

methoxy

α-end

methoxy

α-end

-

α-end

methoxy

应用

聚(乙二醇)甲基醚可作为成孔剂, 以制备亲水性增强的聚砜膜。

聚(乙二醇)甲基醚接枝的聚酰胺 (PAMAM)树枝状聚合物可作为抗癌药物的 载药体系。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(F)

359.6 °F - closed cup

闪点(C)

182 °C - closed cup


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Polyethylene glycol dimethyl ether 500 (stabilised) for synthesis

Sigma-Aldrich

8.14171

聚乙二醇二甲醚500

Smita K Pawar et al.
International journal of pharmaceutics, 436(1-2), 183-193 (2012-06-23)
Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing delivery systems targeted only to cancer cells. Toward this objectives, we propose, synthesis of poly(ethylene glycol) (PEG)-doxorubicin (DOX) prodrug conjugates
Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Junming Li et al.
Journal of biomedical nanotechnology, 8(5), 809-817 (2012-08-15)
In this study, quercetin (QC) with cancer chemoprevention effect and anticancer potential was loaded into polymeric micelles of methoxy poly(ethylene glycol)-cholesterol conjugate (mPEG-Chol) in order to increase its water solubility. MPEG-Chol with lower critical micelle concentration (CMC) value (4.0 x
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier

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