202509

聚乙二醇甲基醚

average M_n ~2,000

• Synonym(s): mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚
• Linear Formula: CH₃(OCH₂CH₂)_nOH
• CAS Number: 9004-74-4
• MDL编号: MFCD00084416
• PubChem化学物质编号: 24852095
• NACRES: NA.23

Properties

• 蒸汽密度: >1 (vs air)
• 质量水平: 200
• 蒸汽压: 0.05 mmHg ( 20 °C)
• 形式: flakes (or pellets)
• 分子量: average M_n ~2,000
• 粘度: 54.6 cSt(210 °F)(lit.)
• 转变温度: T_m 52 °C
• 官能团: hydroxyl
• InChI: 1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
• InChI key: XNWFRZJHXBZDAG-UHFFFAOYSA-N

Description

一般描述

它是聚乙二醇（PEG）大分子单体，具有由甲基醚组成的反应性链端。PEG链末端的醚化可以通过在碱性条件下使其与烷基卤化物进行反应来实现。mPEG可以进行交联以形成水凝胶;聚合反应可以通过氧化还原反应或自由基引发剂进行引发。

应用

Poly(ethylene glycol) methyl ether-attached dendrimers can be used as carriers for anticancer drugs. This novel drug carrier has a biocompatible surface and an interior for the encapsulation of drugs.

It can be used as a pore-forming agent in the preparation of ultrafiltration membranes which are used in the removal of macromolecules.

It can also be used as a starting material in the preparation of a biodegradable amphiphilic copolymer of poly(L-alanine) with mPEG.

特点和优势

Inserting poly(ethylene glycol) methyl ether (mPEG) side chain enhances the hydrophilicity and flexibility of the polymer matrix.

Safety Information

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(F): 359.6 °F - closed cup
• 闪点(C): 182 °C - closed cup
• 个人防护装备: Eyeshields, Gloves