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Merck
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54965

Sigma-Aldrich

(±)-3-羟基丁酸钠

≥99.0% (NT)

别名:

(±)-3-羟基丁酸 钠盐

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About This Item

线性分子式:
CH3CH(OH)CH2COONa
CAS号:
150-83-4
分子量:
126.09
Beilstein:
4824866
EC 号:
205-774-5
MDL编号:
MFCD00016716
UNSPSC代码:
12352100
PubChem化学物质编号:
57651496
NACRES:
NA.22

质量水平

200

方案

≥99.0% (NT)

mp

167-170 °C

官能团

hydroxyl

SMILES字符串

[Na+].CC(O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

应用

（±）-3-羟基丁酸钠已被用于研究，以了解丁酸盐对成纤维细胞生长因子 21（FGF21）的影响，其参与肝脏中的脂肪酸 β-氧化。它可用于制备聚（3-羟基丁酸酯）。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL8810
BCCM2157
BCCK8667
BCCJ4209
BCCH2106

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Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Carolina Akiko Sato Cabral Araújo et al.
PeerJ, 8, e8933-e8933 (2020-04-21)
The end of pregnancy is the period with the highest risk of occurrences of ketosis and pregnancy toxemia due to fat mobilization and increasing non-esterified fatty acids in the liver which are converted in ketone bodies, mainly β-hydroxybutyrate acid (BHB).
Hossein Ghahremani et al.
Galen medical journal, 9, e1831-e1831 (2021-09-02)
Alteration of metabolic pathways in cancer cells can intensely modulate their migration as an important step in invasion and metastasis. Ketogenic diet showed some contradictory results in cancer patients. In this study the impact of metabolic reprogramming of A2780CP as
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
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