578940

Sigma-Aldrich

三--丁基膦四氟硼酸盐

97%

别名:
[(t-Bu)3PH]BF4, TTBP·HBF4
线性分子式:
[[(CH3)3C]3PH]BF4
CAS号:
分子量:
290.13
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

100

测定

97%

reaction suitability

reaction type: Cross Couplings
reagent type: ligand
reaction type: Addition Reactions

reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction

reagent type: ligand
reaction type: Carbonylations

reagent type: ligand
reaction type: Heck Reaction

reagent type: ligand
reaction type: Negishi Coupling

reagent type: ligand
reaction type: Sonogashira Coupling

reagent type: ligand
reaction type: Stille Coupling

reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

mp

261 °C (lit.)

官能团

phosphine

SMILES string

F[B-](F)(F)F.CC(C)(C)[PH+](C(C)(C)C)C(C)(C)C

InChI

1S/C12H27P.BF4/c1-10(2,3)13(11(4,5)6)12(7,8)9;2-1(3,4)5/h1-9H3;/q;-1/p+1

InChI key

YTJUCJAUJCXFTN-UHFFFAOYSA-O

包装

1, 5, 100 g in glass bottle

应用

作为配体用于Pd催化的 N-Boc-吡咯烷的对映选择性α−芳基化反应。
位阻膦盐,与 Pd(0)-15 元三烯酸大环化合物一起用于芳基溴化物和氯化物的 Suzuki 交叉偶联反应。还可用于未活化的甲苯磺酸乙烯酯与缺电子烯烃的 Heck 偶联反应。

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

Heck coupling with nonactivated alkenyl tosylates and phosphates: examples of effective 1,2-migrations of the alkenyl palladium(II) intermediates.
Anders L Hansen et al.
Angewandte Chemie (International ed. in English), 45(20), 3349-3353 (2006-04-12)
Synlett, 3001-3001 (2006)
Kevin R Campos et al.
Journal of the American Chemical Society, 128(11), 3538-3539 (2006-03-16)
This communication discloses the first instance of the enantioselective Pd-catalyzed alpha-arylation of N-Boc-pyrrolidine. The methodology relies on Beak's sparteine-mediated, enantioselective deprotonation of N-Boc-pyrrolidine to form the 2-pyrrolidinolithium specices in high enantiomeric ratio (er). Transmetalation of this intermediate with zinc chloride...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门