671479

Sigma-Aldrich

正丁基二(1-金刚烷基)膦

95%

别名:
cataCXium® A
Empirical Formula (Hill Notation):
C24H39P
CAS号:
分子量:
358.54
Beilstein/REAXYS Number:
8726448
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

100

测定

95%

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

reagent type: ligand
reaction type: Arylations

reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction

reagent type: ligand
reaction type: C-C Bond Formation

reagent type: ligand
reaction type: Heck Reaction

reagent type: ligand
reaction type: Sonogashira Coupling

reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

官能团

phosphine

SMILES string

CCCCP([C@]12C[C@H]3C[C@H](C[C@H](C3)C1)C2)[C@@]45C[C@@H]6C[C@@H](C[C@@H](C6)C4)C5

InChI

1S/C24H39P/c1-2-3-4-25(23-11-17-5-18(12-23)7-19(6-17)13-23)24-14-20-8-21(15-24)10-22(9-20)16-24/h17-22H,2-16H2,1H3/t17-,18+,19-,20-,21+,22-,23-,24-

InChI key

HTJWUNNIRKDDIV-FECFBMJZSA-N

一般描述

与 Solvias AG 联合销售

应用

cataCXium® A或二金刚烷基膦是一种体积庞大且富含电子的膦配体,对钯催化的交叉偶联反应非常有效,例如Heck 和 Suzuki偶联,Buchwald-Hartwig芳基氯化物胺化,和& # 945;酮的芳基化反应。

其他应用:
  • 钯催化的芳基和杂芳基卤化物的羰基化
  • 钯催化的(杂)芳腈的合成
  • 钯催化的芳基卤化物的氨基羰基化

包装

1, 5 g in glass bottle

特点和优势

  • 反应条件温和,
  • 催化剂负载量低,
  • 产率高,转化率高

法律信息

US7148176
cataCXium is a registered trademark of Evonik Degussa GmbH

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

An Efficient and Practical Sequential One-Pot Synthesis of Suprofen, Ketoprofen and Other 2-Arylpropionic Acids
Neumann H, et al.
Advanced Synthesis & Catalysis, 350(14-15), 2437-2442 (2008)
Efficient palladium catalysts for the amination of aryl chlorides: a comparative study on the use of phosphium salts as precursors to bulky, electron-rich phosphines
Tewari, Amit and Hein, Martin and Zapf, Alexander and Beller, Matthias
Tetrahedron, 61(41), 9705-9709 (2005)
An Efficient and Practical Sequential One-Pot Synthesis of Suprofen, Ketoprofen and Other 2-Arylpropionic Acids
Neumann H, et al.
advanced synthesis and catalysis, 350(14-15), 2437-2442 (2008)
A general and efficient method for the formylation of aryl and heteroaryl bromides
Klaus S, et al.
Angewandte Chemie (International Edition in English), 45(1), 154-158 (2006)
Efficient carbonylation of aryl and heteroaryl bromides using a palladium/diadamantylbutylphosphine catalyst
Neumann H, et al.
Advanced Synthesis & Catalysis, 348(10-11), 1255-1261 (2006)
技术文章
cataCXium® - Ligands and Complexes for Efficient Cross-Coupling Reactions. Cross-coupling reactions are an important class of catalytic transformations with applications in polymer science as well as in the fine chemicals and pharmaceutical industries.
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