685089

Sigma-Aldrich

2,2′-[(1R,3R)-2,3,5,10-四氢-5,10-二氧-2-苯基-1H-[1,2,4]二氮杂磷杂环戊烷[1,2-b]酞嗪-1,3-二基]双[N-[(1S)-1-苯乙基]苯甲酰胺]

别名:
(R,R,S)-DiazaPhos-PPE
Empirical Formula (Hill Notation):
C46H39N4O4P
CAS号:
分子量:
742.80
MDL number:
PubChem Substance ID:
NACRES:
NA.22

optical activity

[α]20/D +105°, c = 1 in THF

Quality Level

mp

258-262 °C

SMILES string

C[C@H](NC(=O)c1ccccc1[C@@H]2N3N([C@H](P2c4ccccc4)c5ccccc5C(=O)N[C@@H](C)c6ccccc6)C(=O)c7ccccc7C3=O)c8ccccc8

InChI

1S/C46H39N4O4P/c1-30(32-18-6-3-7-19-32)47-41(51)35-24-12-16-28-39(35)45-49-43(53)37-26-14-15-27-38(37)44(54)50(49)46(55(45)34-22-10-5-11-23-34)40-29-17-13-25-36(40)42(52)48-31(2)33-20-8-4-9-21-33/h3-31,45-46H,1-2H3,(H,47,51)(H,48,52)/t30-,31-,45+,46+/m0/s1

InChI key

XLHCPIVFAWUOET-JBVOVCRZSA-N

Application

二氮杂磷杂环戊烷配体在铑催化的不对称氢甲酰化反应中显示出优良的转化水平和选择性。

Packaging

100 mg in clear glass bottle
500 mg in amber glass bottle

Legal Information

销售的产品仅限于研发目的并且不允许终端用户用于商品生产。与 DowpharmaSM(Dow Chemical Company 的业务单位)联合销售产品。美国专利 7,071,357B。

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Highly regio- and enantioselective asymmetric hydroformylation of olefins mediated by 2,5-disubstituted phospholane ligands.
Alex T Axtell et al.
Angewandte Chemie (International ed. in English), 44(36), 5834-5838 (2005-08-13)
Thomas P Clark et al.
Journal of the American Chemical Society, 127(14), 5040-5042 (2005-04-07)
Azines made by the reaction of hydrazine with ortho-formylbenzoic acid react with 1,2-diphosphinobenzene and either succinyl chloride or phthaloyl chloride in ca. 30% yield to give rac-bis-3,4-diazaphospholanes bearing benzoic acid groups in the 2 and 5 positions. Condensation of the...
技术文章
Diazaphospholane Ligands for Catalytic Asymmetric Transformations: Professor Landis and co-workers developed a series of new ligands based on chiral 3,4-diazaphospholane structures.
了解更多

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。